Mengfan Wu, Zhuang Sun, Peizheng Shi, Ningbin Zhao, Kaiqiang Sun, Chen Ye, He Li, Nan Jiang, Li Fu, Yunlong Zhou, Cheng-Te Lin
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引用次数: 0
Abstract
Oxalic acid (OA) is a predominant constituent in kidney stones, contributing to 70–80% of all cases. Rapid detection of OA is vital for the early diagnosis and treatment of kidney stone conditions. This work introduces a novel electrochemical sensing approach for OA, leveraging vanadium disulfide (VS2) nanoflowers synthesized via hydrothermal synthesis. These VS2 nanoflowers, known for their excellent electrocatalytic properties and large surface area, are used to modify glassy carbon electrodes for enhanced OA sensing. The proposed OA sensor exhibits high sensitivity and selectivity across a wide linear detection range of 0.2–20 μM, with an impressively low detection limit of 0.188 μM. The practicality of this sensor was validated through interference studies, offering a promising tool for the early diagnosis and monitoring of kidney stone diseases.
草酸（OA）是肾结石的主要成分，占所有病例的 70-80%。快速检测草酸对肾结石的早期诊断和治疗至关重要。本研究利用通过水热合成法合成的二硫化二钒（VS2）纳米流体，介绍了一种新型 OA 电化学传感方法。这些二硫化二钒（VS2）纳米流体以其优异的电催化性能和大表面积而著称，被用来修饰玻璃碳电极以增强 OA 传感。所提出的 OA 传感器在 0.2-20 μM 的宽线性检测范围内表现出高灵敏度和高选择性，检测限低至 0.188 μM，令人印象深刻。通过干扰研究验证了该传感器的实用性，为肾结石疾病的早期诊断和监测提供了一种前景广阔的工具。
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