Monte Carlo-based Investigation of Absorbed-dose Energy Dependence of Thermoluminescent Dosimeters in Therapeutic Proton and Carbon Ion Beams.

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal of Medical Physics Pub Date : 2024-04-01 Epub Date: 2024-06-25 DOI:10.4103/jmp.jmp_25_24
Arghya Chattaraj, Subhalaxmi Mishra, T Palani Selvam
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引用次数: 0

Abstract

Background: The present study is aimed at calculating relative absorbed-dose energy response correction (R) of commonly used thermoluminescent dosimeters (TLDs) such as LiF, Li2B4O7, and Al2O3 as a function of depth in water for protons (50-250 MeV/n) and carbon ion (80-480 MeV/n) beams using Monte Carlo-based FLUKA code.

Materials and methods: On-axis depth-dose profiles in water are calculated for protons (50-250 MeV/n) and carbon ion (80-480 MeV/n) beams using FLUKA code. For the calculation of R, selective depths are chosen based on the depth-dose profiles. In the simulations, the TLDs of dimensions 1 mm × 1 mm × 1 mm are positioned at the flat, dose gradient, and Bragg peak regions of the depth-dose profile. Absorbed dose to detector was calculated within the TLD material. In the second step, TLD voxels were replaced by water voxel of similar dimension and absorbed dose to water was scored.

Results: The study reveals that for both proton and carbon ion beams, the value of R differs from unity significantly at the Bragg peak position and is close to unity at the flat region for the investigated TLDs. The calculated R value is sensitive to depth in water, beam energy, type of ion beam, and type of TLD.

Discussion: For accurate dosimetry of protons and carbon ion beams using TLDs, the response of the TLD should be corrected to account for its absorbed-dose energy dependence.

基于蒙特卡洛的治疗质子和碳离子束热释光剂量计吸收剂量能量依赖性研究
背景:本研究旨在使用基于蒙特卡罗的 FLUKA 代码计算常用热释光剂量计(TLD)(如 LiF、Li2B4O7 和 Al2O3)的相对吸收剂量能量响应校正(R)与质子(50-250 MeV/n)和碳离子(80-480 MeV/n)光束在水中深度的函数关系:使用 FLUKA 代码计算质子(50-250 MeV/n)和碳离子(80-480 MeV/n)光束在水中的轴向深度-剂量曲线。在计算 R 时,根据深度-剂量剖面图选择选择性深度。在模拟中,尺寸为 1 mm × 1 mm × 1 mm 的 TLD 位于深度-剂量剖面的平坦、剂量梯度和布拉格峰区域。在 TLD 材料内部计算探测器的吸收剂量。第二步,用类似尺寸的水体体素代替 TLD 体素,并计算水体的吸收剂量:研究表明,对于质子和碳离子束,R 值在布拉格峰位置与统一值相差很大,而在所研究的 TLD 的平坦区域则接近统一值。计算出的 R 值对水深、光束能量、离子束类型和 TLD 类型都很敏感:讨论:为了使用 TLD 对质子和碳离子束进行准确的剂量测定,应校正 TLD 的响应,以考虑其吸收剂量的能量依赖性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Medical Physics
Journal of Medical Physics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.10
自引率
11.10%
发文量
55
审稿时长
30 weeks
期刊介绍: JOURNAL OF MEDICAL PHYSICS is the official journal of Association of Medical Physicists of India (AMPI). The association has been bringing out a quarterly publication since 1976. Till the end of 1993, it was known as Medical Physics Bulletin, which then became Journal of Medical Physics. The main objective of the Journal is to serve as a vehicle of communication to highlight all aspects of the practice of medical radiation physics. The areas covered include all aspects of the application of radiation physics to biological sciences, radiotherapy, radiodiagnosis, nuclear medicine, dosimetry and radiation protection. Papers / manuscripts dealing with the aspects of physics related to cancer therapy / radiobiology also fall within the scope of the journal.
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