The effects of real vs simulated high altitude on associative memory for emotional stimuli

IF 2.4 3区医学 Q2 BEHAVIORAL SCIENCES

Physiology & Behavior Pub Date : 2024-08-09 DOI:10.1016/j.physbeh.2024.114663

Matteo Gatti , Giulia Prete , David Perpetuini , Danilo Bondi , Vittore Verratti , Fulvia Quilici Matteucci , Carmen Santangelo , Salvatore Annarumma , Adolfo Di Crosta , Rocco Palumbo , Arcangelo Merla , Giuseppe Costantino Giaconia , Luca Tommasi , Nicola Mammarella

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引用次数: 0

Abstract

Introduction

This study aimed to investigate the effects of normobaric hypoxia (NH) and hypobaric hypoxia (HH) on associative memory performance for emotionally valenced stimuli.

Methods

Two experiments were conducted. In Study 1, n = 18 undergraduates performed an associative memory task under three NH conditions (FiO₂= 20.9 %, 15.1 %, 13.6 %) using a tent with a hypoxic generator. In Study 2, n = 20 participants were assessed in a field study at various altitudes on the Himalayan mountains, including the Pyramid Laboratory (5000 m above sea level), using functional Near-Infrared Spectroscopy (fNIRS) and behavioral assessments.

Results

Study 1 revealed no significant differences in recognition accuracy across NH conditions. However, Study 2 showed a complex relationship between altitude and memory for emotionally valenced stimuli. At lower altitudes, participants more accurately recognized emotional stimuli compared to neutral ones, a trend that reversed at higher altitudes. Brain oxygenation varied with altitude, indicating adaptive cognitive processing, as revealed by fNIRS measurements.

Conclusions

These findings suggest that hypoxia affects associative memory and emotional processing in an altitude-dependent manner, highlighting adaptive cognitive mechanisms. Understanding the effects of hypobaric hypoxia on cognition and memory can help develop strategies to mitigate its impact in high-altitude and hypoxic environments.

查看原文本刊更多论文

真实高海拔与模拟高海拔对情绪刺激联想记忆的影响。

研究简介本研究旨在探讨常压缺氧（NH）和低压缺氧（HH）对情绪化刺激联想记忆能力的影响：方法：进行了两项实验。在研究 1 中，18 名本科生在三个 NH 条件（FiO2= 20.9%、15.1%、13.6%）下使用带低氧发生器的帐篷完成了联想记忆任务。在研究 2 中，20 名参与者在喜马拉雅山脉的不同海拔高度（包括金字塔实验室（海拔 5000 米））进行了实地研究，并使用功能性近红外光谱仪（fNIRS）和行为评估进行了评估：研究 1 显示，不同 NH 条件下的识别准确率没有明显差异。然而，研究 2 表明海拔高度与情绪价值刺激记忆之间存在复杂的关系。与中性刺激相比，海拔较低时，受试者能更准确地识别情绪刺激，而海拔较高时，这一趋势发生逆转。脑氧饱和度随海拔高度的变化而变化，这表明认知过程具有适应性，fNIRS测量也揭示了这一点：这些研究结果表明，缺氧会以海拔依赖性的方式影响联想记忆和情感处理，突出了适应性认知机制。了解低气压缺氧对认知和记忆的影响有助于制定策略，减轻其在高海拔和缺氧环境中的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Physiology & Behavior 医学-行为科学

CiteScore

5.70

自引率

3.40%

发文量

274

审稿时长

47 days

期刊介绍： Physiology & Behavior is aimed at the causal physiological mechanisms of behavior and its modulation by environmental factors. The journal invites original reports in the broad area of behavioral and cognitive neuroscience, in which at least one variable is physiological and the primary emphasis and theoretical context are behavioral. The range of subjects includes behavioral neuroendocrinology, psychoneuroimmunology, learning and memory, ingestion, social behavior, and studies related to the mechanisms of psychopathology. Contemporary reviews and theoretical articles are welcomed and the Editors invite such proposals from interested authors.