Microencapsulation of natural products using spray drying; an overview.

IF 3 4区医学 Q2 CHEMISTRY, APPLIED

Journal of microencapsulation Pub Date : 2024-11-01 Epub Date: 2024-08-12 DOI:10.1080/02652048.2024.2389136

Mahshid Mardani, Saeed Siahtiri, Masoud Besati, Mostafa Baghani, Majid Baniassadi, Alireza Mahdavi Nejad

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引用次数: 0

Abstract

Aims: This study examines microencapsulation as a method to enhance the stability of natural compounds, which typically suffer from inherent instability under environmental conditions, aiming to extend their application in the pharmaceutical industry.

Methods: We explore and compare various microencapsulation techniques, including spray drying, freeze drying, and coacervation, with a focus on spray drying due to its noted advantages.

Results: The analysis reveals that microencapsulation, especially via spray drying, significantly improves natural compounds' stability, offering varied morphologies, sizes, and efficiencies in encapsulation. These advancements facilitate controlled release, taste modification, protection from degradation, and extended shelf life of pharmaceutical products.

Conclusion: Microencapsulation, particularly through spray drying, presents a viable solution to the instability of natural compounds, broadening their application in pharmaceuticals by enhancing protection and shelf life.

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利用喷雾干燥技术对天然产品进行微胶囊化；概述。

目的：本研究将微胶囊技术作为一种提高天然化合物稳定性的方法进行探讨，天然化合物在环境条件下通常具有固有的不稳定性，本研究旨在扩大天然化合物在制药业的应用：方法：我们探讨并比较了各种微胶囊技术，包括喷雾干燥、冷冻干燥和共凝，其中喷雾干燥因其显著的优点而受到关注：结果：分析表明，微胶囊技术，尤其是喷雾干燥技术，能显著提高天然化合物的稳定性，并提供不同的形态、大小和封装效率。这些进步有助于控制释放、改变口味、防止降解和延长药品的保质期：结论：微胶囊技术，尤其是喷雾干燥技术，为解决天然化合物的不稳定性问题提供了一种可行的解决方案，通过加强保护和延长保质期，扩大了天然化合物在药品中的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of microencapsulation 工程技术-工程：化工

CiteScore

6.30

自引率

2.60%

发文量

审稿时长

3 months

期刊介绍： The Journal of Microencapsulation is a well-established, peer-reviewed journal dedicated to the publication of original research findings related to the preparation, properties and uses of individually encapsulated novel small particles, as well as significant improvements to tried-and-tested techniques relevant to micro and nano particles and their use in a wide variety of industrial, engineering, pharmaceutical, biotechnology and research applications. Its scope extends beyond conventional microcapsules to all other small particulate systems such as self assembling structures that involve preparative manipulation. The journal covers: Chemistry of encapsulation materials Physics of release through the capsule wall and/or desorption from carrier Techniques of preparation, content and storage Many uses to which microcapsules are put.