Polysomnographic features prior to dream enactment behaviors in isolated rapid eye movement sleep behavior disorder

IF 3.7 3区医学 Q1 CLINICAL NEUROLOGY

Clinical Neurophysiology Pub Date : 2024-07-31 DOI:10.1016/j.clinph.2024.07.013

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引用次数: 0

Abstract

Objective

This study aimed to identify electroencephalogram correlates of dream enactment behaviors (DEBs) and elucidate their cortical dynamics in patients with isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD).

Methods

This cross-sectional study included 15 patients with iRBD. Two REM sleep periods in routine polysomnography were compared: the 60 s preceding the DEBs (“pre-representative behavior” [preR]), and the 60 s with the least submental electromyogram activity (“background” [BG]). Six EEG frequency bands and electrooculogram were analyzed; power spectra, coherence and phase-locking values in four 15-s periods were examined to assess trends. These indices were also compared between preR and BG.

Results

Compared with BG, significantly higher delta power in the F3 channel and gamma power in the F4 and O2 channels were observed during preR. For functional connectivity, the widespread beta-band connectivity was significantly increased during preR than BG.

Conclusion

Before notable REM sleep behaviors, uneven distributed higher EEG spectral power in both very low and high frequencies, and increased wide-range beta band functional connectivity, were observed over 60 s, suggesting cortical correlates to subsequent DEBs.

Significance

This study may shed light on the pathological mechanisms underlies RBD through the routine vPSG analysis, leading to detection of DEBs.

查看原文本刊更多论文

孤立性快速眼动睡眠行为障碍患者做梦前的多导睡眠图特征。

研究目的本研究旨在识别脑电图与做梦行为（DEB）的相关性，并阐明孤立性/特发性快速眼动（REM）睡眠行为障碍（iRBD）患者大脑皮层的动态变化：这项横断面研究包括15名iRBD患者。方法：这项横断面研究纳入了 15 名 iRBD 患者，对常规多导睡眠图中的两个快速眼动睡眠期进行了比较：DEBs 之前的 60 秒（"前表现行为"[pre-R]）和门下肌电图活动最少的 60 秒（"背景"[BG]）。对六个脑电图频段和脑电图进行了分析；对四个 15 秒周期的功率谱、相干性和锁相值进行了检查，以评估趋势。这些指数还在 PR 和 BG 之间进行了比较：结果：与 BG 相比，前 R 期间 F3 通道的 delta 功率以及 F4 和 O2 通道的 gamma 功率明显更高。在功能连通性方面，preR期间广泛的β波段连通性明显高于BG期间：结论：在明显的快速眼动睡眠行为之前，60 秒内观察到分布不均的极低频和高频较高的脑电图频谱功率，以及范围广泛的 beta 波段功能连接性增加，这表明大脑皮层与随后的 DEBs 相关：本研究可通过常规 vPSG 分析揭示 RBD 的病理机制，从而发现 DEBs。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Neurophysiology 医学-临床神经学

CiteScore

8.70

自引率

6.40%

发文量

932

审稿时长

59 days

期刊介绍： As of January 1999, The journal Electroencephalography and Clinical Neurophysiology, and its two sections Electromyography and Motor Control and Evoked Potentials have amalgamated to become this journal - Clinical Neurophysiology. Clinical Neurophysiology is the official journal of the International Federation of Clinical Neurophysiology, the Brazilian Society of Clinical Neurophysiology, the Czech Society of Clinical Neurophysiology, the Italian Clinical Neurophysiology Society and the International Society of Intraoperative Neurophysiology.The journal is dedicated to fostering research and disseminating information on all aspects of both normal and abnormal functioning of the nervous system. The key aim of the publication is to disseminate scholarly reports on the pathophysiology underlying diseases of the central and peripheral nervous system of human patients. Clinical trials that use neurophysiological measures to document change are encouraged, as are manuscripts reporting data on integrated neuroimaging of central nervous function including, but not limited to, functional MRI, MEG, EEG, PET and other neuroimaging modalities.

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