Checkmate 77T: Perioperative chemoimmunotherapy outperforms in early-stage NSCLC.

IF 12.8 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Med Pub Date : 2024-08-09 DOI:10.1016/j.medj.2024.06.012

Danielle Brazel, Misako Nagasaka

引用次数: 0

Abstract

Approximately 1 in 4 patients with NSCLC present with resectable disease. Although surgery is potentially curative, 30%-50% of patients relapse. Studies have shown that neoadjuvant, adjuvant, and perioperative chemoimmunotherapy improve outcomes. The Checkmate 77T trial explored if perioperative platinum-based chemotherapy plus nivolumab, surgical resection, then adjuvant nivolumab further improved outcomes including EFS.¹.

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Checkmate 77T：围手术期化学免疫疗法在早期 NSCLC 中表现优异。

大约每 4 名 NSCLC 患者中就有 1 人患有可切除的疾病。虽然手术有可能治愈，但仍有 30%-50% 的患者会复发。研究表明，新辅助治疗、辅助治疗和围手术期化疗免疫疗法可改善预后。Checkmate 77T 试验探讨了围手术期铂类化疗加尼夫单抗、手术切除、然后辅助尼夫单抗是否能进一步改善包括 EFS 在内的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Med MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

17.70

自引率

0.60%

发文量

102

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