Role of Computed Tomography in Prediction of Depth of Invasion and Cervical Lymph Node Metastasis in Oral Cancer.

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Maxillofacial & Oral Surgery Pub Date : 2024-08-01 Epub Date: 2024-06-19 DOI:10.1007/s12663-024-02265-7

Viswanth Kottakota, Dibya Falgoon Sarkar, V N Saratchandu Tadepalli, Vijaya Aditya Yadaraju, Kalla B Muralidhar, Sanketh Kotne, Muralidhar Bora, Perraju Bhaskar Bhuvan Lagudu

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引用次数: 0

Abstract

Objectives: The primary aim is to determine the accuracy of contrast-enhanced computed tomography (CT) in evaluation of depth of invasion (DOI) and detection of cervical node metastasis. We also analysed the relation between radiographic DOI (rDOI) and cervical lymph node metastasis.

Materials and methods: We have retrospectively reviewed 201 oral squamous cell carcinoma (SCC) patients. The rDOI was compared with histological DOI. Sensitivity, specificity, accuracy, and negative (NPV) and positive (PPV) predictive values were evaluated for CT scan in predicting nodal metastasis. The relation between rDOI and lymph node metastasis was analysed using ROC curve.

Results: rDOI correlated significantly with histologic DOI for oral tongue, buccal mucosa, gingiva, and mucosal lip SCC (P < 0.05) and for tumours with rDOI > 5 mm. The sensitivity, specificity, PPV, NPV and accuracy rate of CT scan were found to be 84.71%, 50.86%, 55.81%, 81.94% and 65.17%, respectively. Tumours with rDOI > 16 mm had significant (P < 0.001) chance of having neck node metastasis.

Conclusion: CT-derived DOI correlates significantly with pathological DOI although both are not similar. CT scan can predict nodal metastasis in fairly accurate manner using the four radiographic criteria used in this study. Radiographic depth of invasion can be used as predictor of cervical node metastasis.

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计算机断层扫描在预测口腔癌浸润深度和颈淋巴结转移中的作用

研究目的主要目的是确定对比增强计算机断层扫描（CT）在评估浸润深度（DOI）和检测宫颈结节转移方面的准确性。我们还分析了放射学 DOI（rDOI）与宫颈淋巴结转移之间的关系：我们对 201 例口腔鳞状细胞癌（SCC）患者进行了回顾性研究。将 rDOI 与组织学 DOI 进行了比较。评估了 CT 扫描预测结节转移的敏感性、特异性、准确性、阴性预测值（NPV）和阳性预测值（PPV）。结果：对于口腔舌、口腔粘膜、牙龈和唇粘膜 SCC，rDOI 与组织学 DOI 显著相关（P 5 mm）。CT 扫描的敏感性、特异性、PPV、NPV 和准确率分别为 84.71%、50.86%、55.81%、81.94% 和 65.17%。rDOI>16毫米的肿瘤与CT得出的DOI有显著的相关性：CT得出的DOI与病理DOI有明显相关性，但两者并不相似。使用本研究中使用的四种放射学标准，CT 扫描可以相当准确地预测结节转移。放射学侵袭深度可作为宫颈结节转移的预测指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Maxillofacial & Oral Surgery DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

1.90

自引率

0.00%

发文量

138

期刊介绍： This journal offers comprehensive coverage of new techniques, important developments and innovative ideas in Oral and Maxillofacial Surgery. Practice-applicable articles help develop the methods used to handle dentoalveolar surgery, facial injuries and deformities, TMJ disorders, oral cancer, jaw reconstruction, anesthesia and analgesia. The journal also includes specifics on new instruments, diagnostic equipment’s and modern therapeutic drugs and devices. Journal of Oral and Maxillofacial Surgery is recommended for first or priority subscription by the Dental Section of the Medical Library Association. Specific topics covered recently have included: ? distraction osteogenesis ? synthetic bone substitutes ? fibroblast growth factors ? fetal wound healing ? skull base surgery ? computer-assisted surgery ? vascularized bone grafts Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.