Pediatric Cystic Echinococcosis in Tehran, Iran: A 9-Year Retrospective Epidemiological and Clinical Survey of Hospitalized Cases.

IF 1.9 2区 农林科学 Q3 FOOD SCIENCE & TECHNOLOGY
Foodborne pathogens and disease Pub Date : 2024-10-01 Epub Date: 2024-08-09 DOI:10.1089/fpd.2024.0034
Shima Mahmoudi, Mina Dolatzadeh, Gita Manzari Tavakoli, Babak Pourakbari, Mohammad Reza Abdolsalehi, Setareh Mamishi
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Abstract

Cystic echinococcosis (CE), the second most significant foodborne parasitic disease worldwide, poses a significant global health burden. Understanding its clinical and laboratory features is crucial for effective management. This study aimed to investigate the epidemiological, laboratory, and clinical characteristics of pediatric CE in an Iranian referral hospital. A cross-sectional study reviewed hospital records of patients with CE admitted to Children's Medical Center, Tehran, Iran, from 2011 to 2020. Data on demographics, diagnostics, clinical presentation, laboratory findings, and treatment were collected and analyzed. A total of 114 patients, with a mean age of 7.33 ± 2.9 years, were diagnosed with CE. The male-to-female ratio was 1.78, and 73.7% were urban residents. Abdominal pain (69%) and coughing (65%) were the most common symptoms. In confirming the cyst involvement across anatomical sites, pathology emerged as the most reliable method, with effectiveness ranging from 95% to 100%. Abdominal ultrasonography and computed tomography scan were frequently utilized imaging modalities, displaying effectiveness percentages of 71-85%. Liver and lung involvement predominated (66%), with 39% of cases showing multiorgan involvement. Spleen involvement was less common (6%), and neurological involvement was rare (1-2%). The majority of patients (n = 63, 67.7%) displayed cysts larger than 50 mm. All patients received albendazole treatment, and 104 patients (91.2%) underwent surgical procedures, with three postsurgical deaths. In conclusion, hospital records over 9 years indicate an increasing prevalence of CE, emphasizing the need for heightened awareness and effective public health interventions to control this parasitic infection.

伊朗德黑兰的小儿囊性棘球蚴病:对住院病例的 9 年回顾性流行病学和临床调查。
囊性棘球蚴病(CE)是全球第二大食源性寄生虫病,给全球健康造成了巨大负担。了解其临床和实验室特征对于有效管理至关重要。本研究旨在调查伊朗一家转诊医院中小儿棘球蚴病的流行病学、实验室和临床特征。这项横断面研究回顾了伊朗德黑兰儿童医学中心 2011 年至 2020 年收治的 CE 患者的住院记录。研究收集并分析了有关人口统计学、诊断、临床表现、实验室检查结果和治疗的数据。共有 114 名患者被确诊为 CE,平均年龄(7.33±2.9)岁。男女比例为 1.78,73.7% 为城市居民。腹痛(69%)和咳嗽(65%)是最常见的症状。在确认囊肿累及解剖部位时,病理检查是最可靠的方法,有效率从 95% 到 100% 不等。腹部超声波检查和计算机断层扫描是常用的影像学检查方法,有效率为 71%-85%。肝脏和肺部受累占多数(66%),39%的病例显示多器官受累。脾脏受累较少(6%),神经系统受累罕见(1-2%)。大多数患者(n = 63,67.7%)的囊肿大于 50 毫米。所有患者都接受了阿苯达唑治疗,104 名患者(91.2%)接受了手术治疗,其中 3 人术后死亡。总之,9年来的医院记录表明,CE的发病率在不断上升,这强调了需要提高人们的认识,并采取有效的公共卫生干预措施来控制这种寄生虫感染。
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来源期刊
Foodborne pathogens and disease
Foodborne pathogens and disease 医学-食品科技
CiteScore
5.30
自引率
3.60%
发文量
80
审稿时长
1 months
期刊介绍: Foodborne Pathogens and Disease is one of the most inclusive scientific publications on the many disciplines that contribute to food safety. Spanning an array of issues from "farm-to-fork," the Journal bridges the gap between science and policy to reduce the burden of foodborne illness worldwide. Foodborne Pathogens and Disease coverage includes: Agroterrorism Safety of organically grown and genetically modified foods Emerging pathogens Emergence of drug resistance Methods and technology for rapid and accurate detection Strategies to destroy or control foodborne pathogens Novel strategies for the prevention and control of plant and animal diseases that impact food safety Biosecurity issues and the implications of new regulatory guidelines Impact of changing lifestyles and consumer demands on food safety.
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