Management of acute uncomplicated diverticulitis and adherence to current guidelines-a multicentre SNAPSHOT study.

IF 2.5 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

International Journal of Colorectal Disease Pub Date : 2024-08-08 DOI:10.1007/s00384-024-04701-z

Helene R Dalby, Alessandro Orrú, Frida Sundh, Pamela Buchwald, Fredrik Brännström, Bengt Hansske, Staffan Haapaniemi, Maziar Nikberg, Abbas Chabok

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引用次数: 0

Abstract

Purpose: To explore whether previous participation in clinical studies increases adherence to management guidelines in acute uncomplicated diverticulitis (AUD).

Methods: This retrospective cohort study was designed to give a SNAPSHOT of the management of AUD at six hospitals, three of which had participated in the AVOD trial comparing antibiotic versus non-antibiotic treatment of AUD. Patients with AUD were included from March 2019 through June 2020 and followed for 90 days. The primary outcome was treatment of AUD categorised by antibiotic treatment and inpatient or outpatient management compared between AVOD and non-AVOD hospitals. Descriptive statistics were compiled, and differences between hospitals were assessed with Pearson's chi-squared test.

Results: The cohort included 449 patients with AUD of which 63% were women and the median age was 63 (IQR: 52-73) years. Patient characteristics were comparable across the hospitals. Antibiotics were administered to 84 (19%) patients and 113 (25%) patients were managed as inpatients. Management varied significantly between AVOD and non-AVOD hospitals. The mean proportion of patients treated with antibiotics was 7% at AVOD hospitals compared to 38% at non-AVOD hospitals (p < 0.001). The mean proportion of in-hospital management was 18% at AVOD hospitals versus 38% at non-AVOD hospitals (p < 0.001).

Conclusion: Most patients with AUD were managed according to current guidelines. However, the management varies between hospitals and previous participation in clinical studies may increase knowledge of and adherence to guidelines.

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急性无并发症憩室炎的处理和现行指南的遵守情况--一项多中心 SNAPSHOT 研究。

目的：探讨曾参与临床研究是否会提高急性无并发症憩室炎（AUD）患者对管理指南的依从性：这项回顾性队列研究旨在对六家医院的急性无并发症憩室炎治疗情况进行 "快照"（SNAPSHOT），其中三家医院参与了比较抗生素与非抗生素治疗急性无并发症憩室炎的 AVOD 试验。从 2019 年 3 月到 2020 年 6 月，AUD 患者被纳入其中，并随访 90 天。主要研究结果是，AVOD 医院与非 AVOD 医院对 AUD 的治疗情况进行了比较，分为抗生素治疗、住院或门诊治疗。研究人员编制了描述性统计资料，并通过皮尔逊卡方检验评估了医院之间的差异：研究对象包括 449 名 AUD 患者，其中 63% 为女性，中位年龄为 63 岁（IQR：52-73）。各家医院的患者特征具有可比性。84名（19%）患者接受了抗生素治疗，113名（25%）患者接受了住院治疗。AVOD 医院和非 AVOD 医院之间的管理差异很大。接受抗生素治疗的患者平均比例在 AVOD 医院为 7%，而在非 AVOD 医院则为 38% （P，结论）：大多数 AUD 患者都按照现行指南进行了治疗。然而，不同医院的管理方法各不相同，而之前参与的临床研究可提高对指南的了解和遵守程度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Colorectal Disease 医学-外科

CiteScore

4.90

自引率

3.60%

发文量

206

审稿时长

3-8 weeks

期刊介绍： The International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles, the following categories will be included: reviews (usually commissioned but may also be submitted), case reports, letters to the editor, and protocols on clinical studies. The journal offers its readers an interdisciplinary forum for clinical science and molecular research related to gastrointestinal disease.