Health-related quality of life assessment in health economic analyses involving type 2 diabetes

IF 3.2 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Hayley Smith, Steven James, Fran Brown, Michele Gaca, David O'Neal, An Tran-Duy, Nancy Devlin, Ray Kelly, Elif I. Ekinci
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Abstract

Aim

Incorporating health-related quality of life (HRQoL) measures into health economic analyses can help to provide evidence to inform decisions about how to improve patient outcomes in the most cost-effective manner. The aim of this narrative review was to assess which HRQoL instruments have been used in economic evaluations of type 2 diabetes management including in Indigenous communities.

Method

MEDLINE (Ovid), Embase (Ovid) and Cochrane were searched from inception to June 2022. Studies included patients with type 2 diabetes; economic evaluations, derived scores from direct questioning of individuals; and were in English. Records were assessed for bias using the JBI critical appraisal tools.

Results

A total of 3737 records were identified, with 22 publications meeting the criteria for inclusion. Across those 22 articles, nine HRQoL instruments had been utilised. Generic tools were most frequently used to measure HRQoL, including EQ-5D (−3 L and −5 L) (n = 10, 38%); SF-12 (n = 5, 19%); and SF-36 (n = 4, 15%). Two tools addressing the specific stressors faced by people with type 2 diabetes were utilised: Problem Areas In Diabetes tool (n = 1, 4%) and Diabetes Distress Scale (n = 1, 4%). Two publications reported whether the study population included Indigenous peoples.

Conclusion

A wide range of HRQoL instruments are used in economic evaluations of type 2 diabetes management, with the most frequent being varying forms of the EQ-5D. Few economic evaluations noted whether Indigenous peoples were featured in the study population. More research into HRQoL in people living with type 2 diabetes is urgently needed to improve evidence on effectiveness and cost-effectiveness of interventions.

Abstract Image

2 型糖尿病健康经济分析中与健康相关的生活质量评估。
目的:将与健康相关的生活质量(HRQoL)测量纳入卫生经济分析有助于提供证据,为如何以最具成本效益的方式改善患者预后提供决策依据。本综述旨在评估哪些 HRQoL 工具已用于 2 型糖尿病管理(包括土著社区)的经济评估:方法:检索了从开始到 2022 年 6 月的 MEDLINE (Ovid)、Embase (Ovid) 和 Cochrane。研究对象包括 2 型糖尿病患者、经济评估、通过直接询问个人得出的分数、英语。使用 JBI 关键评估工具对记录进行偏倚评估:结果:共发现 3737 条记录,其中 22 篇符合纳入标准。在这 22 篇文章中,共使用了 9 种 HRQoL 工具。通用工具最常用于测量 HRQoL,包括 EQ-5D(-3 L 和 -5 L)(n = 10,38%)、SF-12(n = 5,19%)和 SF-36(n = 4,15%)。针对 2 型糖尿病患者面临的特定压力,使用了两种工具:糖尿病问题领域工具(n = 1,4%)和糖尿病压力量表(n = 1,4%)。两篇出版物报告了研究人群中是否包括土著居民:结论:在 2 型糖尿病管理的经济评价中使用了多种 HRQoL 工具,其中最常用的是不同形式的 EQ-5D 工具。很少有经济评价指出研究人群中是否包括土著居民。迫切需要对 2 型糖尿病患者的 HRQoL 进行更多的研究,以提高干预措施的有效性和成本效益。
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来源期刊
Diabetic Medicine
Diabetic Medicine 医学-内分泌学与代谢
CiteScore
7.20
自引率
5.70%
发文量
229
审稿时长
3-6 weeks
期刊介绍: Diabetic Medicine, the official journal of Diabetes UK, is published monthly simultaneously, in print and online editions. The journal publishes a range of key information on all clinical aspects of diabetes mellitus, ranging from human genetic studies through clinical physiology and trials to diabetes epidemiology. We do not publish original animal or cell culture studies unless they are part of a study of clinical diabetes involving humans. Categories of publication include research articles, reviews, editorials, commentaries, and correspondence. All material is peer-reviewed. We aim to disseminate knowledge about diabetes research with the goal of improving the management of people with diabetes. The journal therefore seeks to provide a forum for the exchange of ideas between clinicians and researchers worldwide. Topics covered are of importance to all healthcare professionals working with people with diabetes, whether in primary care or specialist services. Surplus generated from the sale of Diabetic Medicine is used by Diabetes UK to know diabetes better and fight diabetes more effectively on behalf of all people affected by and at risk of diabetes as well as their families and carers.”
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