Exploring Uncommon Neurologic Complication in Young Diabetics with Osmotic Demyelination Syndrome: A Case Series and Literature Review.

IF 1.9 4区医学 Q3 CLINICAL NEUROLOGY

Annals of Indian Academy of Neurology Pub Date : 2024-08-08 DOI:10.4103/aian.aian_390_24

Manisha Gupta, Ramesh Gurjar, Arpit Agrawal, Abhijeet Kumar Kohat, Abhishek Kumar

引用次数: 0

Abstract

Abstract: Osmotic demyelination syndrome (ODS) is well known to be associated with the rapid correction of hyponatremia. However, there is limited literature on its link to persistent or corrected hyperglycemic states in diabetic patients. We report two young patients with ODS and hyperglycemia. Neuroimaging and blood tests indicated central pontine and extrapontine myelinolysis with a hyperglycemic hyperosmolar state (HHS). These unusual cases provide insight into the neurologic complications of hyperglycemia.

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探索患有渗透性脱髓鞘综合征的年轻糖尿病患者的罕见神经并发症：病例系列和文献综述。

摘要：众所周知，渗透性脱髓鞘综合征（ODS）与低钠血症的快速纠正有关。然而，有关其与糖尿病患者持续或纠正的高血糖状态之间联系的文献却很有限。我们报告了两名患有 ODS 和高血糖的年轻患者。神经影像学检查和血液化验结果表明，他们患有中枢性桥脑和桥体外髓鞘溶解症，并伴有高血糖高渗状态（HHS）。这些不寻常的病例让我们对高血糖引起的神经系统并发症有了更深入的了解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Indian Academy of Neurology Nervous System Diseases-

CiteScore

2.20

自引率

11.80%

发文量

293

审稿时长

29 weeks

期刊介绍： The journal has a clinical foundation and has been utilized most by clinical neurologists for improving the practice of neurology. While the focus is on neurology in India, the journal publishes manuscripts of high value from all parts of the world. Journal publishes reviews of various types, original articles, short communications, interesting images and case reports. The journal respects the scientific submission of its authors and believes in following an expeditious double-blind peer review process and endeavors to complete the review process within scheduled time frame. A significant effort from the author and the journal perhaps enables to strike an equilibrium to meet the professional expectations of the peers in the world of scientific publication. AIAN believes in safeguarding the privacy rights of human subjects. In order to comply with it, the journal instructs all authors when uploading the manuscript to also add the ethical clearance (human/animals)/ informed consent of subject in the manuscript. This applies to the study/case report that involves animal/human subjects/human specimens e.g. extracted tooth part/soft tissue for biopsy/in vitro analysis.