Predictors of Inflammation-Mediated Preterm Birth.

IF 5.3 2区 医学 Q1 PHYSIOLOGY
Physiology Pub Date : 2025-01-01 Epub Date: 2024-08-06 DOI:10.1152/physiol.00022.2024
Hanah M Georges, Errol R Norwitz, Vikki M Abrahams
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引用次数: 0

Abstract

Preterm birth remains a worldwide health concern because of ongoing challenges in prediction and prevention. Current predictors are limited by poor performance, need for invasive sampling, and an inability to identify patients in a timely fashion to allow for effective intervention. The multiple etiologies of preterm birth often have an inflammatory component. Thus, a deeper understanding of the inflammatory mechanisms involved in preterm birth may provide opportunities to identify new predictors of preterm birth. This review discusses the multiple etiologies of preterm birth, their links to inflammation, current predictors available, and new directions for the field.

炎症引发早产的预测因素
由于在预测和预防方面一直存在挑战,早产仍然是全球关注的健康问题。目前的预测指标性能不佳,需要进行侵入性采样,而且无法及时发现患者以进行有效干预。早产的多种病因通常都有炎症因素。因此,深入了解早产所涉及的炎症机制可为确定新的早产预测指标提供机会。本综述将讨论早产的多种病因、它们与炎症的联系、目前可用的预测指标以及该领域的新方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Physiology
Physiology 医学-生理学
CiteScore
14.50
自引率
0.00%
发文量
37
期刊介绍: Physiology journal features meticulously crafted review articles penned by esteemed leaders in their respective fields. These articles undergo rigorous peer review and showcase the forefront of cutting-edge advances across various domains of physiology. Our Editorial Board, comprised of distinguished leaders in the broad spectrum of physiology, convenes annually to deliberate and recommend pioneering topics for review articles, as well as select the most suitable scientists to author these articles. Join us in exploring the forefront of physiological research and innovation.
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