Implementing pharmacogenomic testing in Australian general practice: an exploratory qualitative study.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-01-01 Epub Date: 2024-08-07 DOI:10.1080/14622416.2024.2382078
Emma Ewasiuk, Jon Emery, Gabrielle Reid, Sibel Saya
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引用次数: 0

Abstract

Aim: To explore general practitioners' (GPs) views on implementing pharmacogenomic testing in Australian general practice.Methods: Semi-structured interviews were conducted with nine GPs in Australia, recruited from primary care networks. Interviews were analyzed using thematic analysis. Themes were mapped onto the Consolidated Framework for Implementation Research domains.Results: Barriers to implementation included lack of knowledge, education, standardized pharmacogenomic reports and national clinical guidelines and financial inaccessibility. Facilitators included positive exposure to pharmacogenomics, peer influences, interdisciplinary collaboration and proven clinical utility. Current uptake was minimal; however, GPs shared positive perceptions of clinical use.Conclusion: Recommendations for successful implementation include building and disseminating clinical evidence, developing national guidelines and standardized reports, incorporation into formal education and increasing financial accessibility.

在澳大利亚全科医生中实施药物基因组测试:一项探索性定性研究。
目的:探讨全科医生(GPs)对在澳大利亚全科实践中实施药物基因组学检测的看法。方法:从初级保健网络中招募了九名澳大利亚全科医生,对他们进行了半结构化访谈:对从初级保健网络中招募的九名澳大利亚全科医生进行了半结构化访谈。采用主题分析法对访谈进行了分析。将主题映射到实施研究领域综合框架中。结果显示实施障碍包括缺乏知识、教育、标准化药物基因组学报告和国家临床指南,以及经济上的不便。促进因素包括积极接触药物基因组学、同行影响、跨学科合作以及经证实的临床效用。然而,全科医生都对临床应用持积极态度。结论:成功实施的建议包括建立和传播临床证据、制定国家指南和标准化报告、将其纳入正规教育以及提高经济可及性。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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