Comparison of Clinical Therapeutic Efficacy between TUPKP and HoLEP for Patients Aged 70 Years and Older with Benign Prostatic Hyperplasia: Retrospective Study.

IF 0.6 4区 医学 Q4 UROLOGY & NEPHROLOGY
Jian Wu, Shuhuang Chen, Xiubin Ye, Zheying Ouyang, Renrui Kuang
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引用次数: 0

Abstract

Objective: The occurrence of prostate hyperplasia has increased remarkedly, especially in elderly patients; However, research on which surgical treatment is effective and safe for benign prostatic hyperplasia (BPH) in elderly people over 70 years old is limited. This study aimed to investigate the clinical efficacy and safety of transurethral plasma kinetic prostatectomy (TUPKP) and holmium laser enucleation of prostate (HoLEP) as a therapy for benign prostatic hyperplasia (BPH) in the elderly.

Methods: A total of 148 patients with BPH admitted from December 2022 to December 2023 were chosen and divided into HoLEP (n = 74) and TUPKP (n = 74) groups according to the surgical operation. Perioperative related indexes, preoperative and postoperative international prostate symptom scores and life quality scores were compared between the two groups. The postoperative complications were also counted for the two groups.

Results: The HoLEP group had lower intraoperative bleeding, mean operative time, catheter indwelling time and hospital stays than the TUPKP group (p < 0.001). Before treatment, no significant difference in prostate symptom scores was found between the two groups (p > 0.05). After treatment, the prostate symptom scores in the HoLEP group were significantly lower than those in the TUPKP group (p < 0.001). However, the maximum urinary flow rate was significantly higher (p < 0.001) and the residual urine volume was significantly lower (p < 0.001) in the HoLEP group than in the TUPKP group after operation. The complication rate in the TUPKP group was 25.66%, which was significantly higher than the 9.46% in the HoLEP group (p < 0.05). The life quality scores of the HoLEP group were higher than those of the TUPKP group (p < 0.001).

Conclusions: HoLEP for BPH therapy is effective and safe with low incidence of postoperative complications.

TUPKP与HoLEP对70岁及以上良性前列腺增生患者的临床疗效比较:回顾性研究。
目的:前列腺增生症的发病率显著增加,尤其是在老年患者中;然而,对于 70 岁以上老年人良性前列腺增生症(BPH),哪种手术治疗方法有效且安全的研究却很有限。本研究旨在探讨经尿道等离子动力前列腺切除术(TUPKP)和前列腺钬激光去核术(HoLEP)治疗老年良性前列腺增生症(BPH)的临床疗效和安全性:选择2022年12月至2023年12月收治的148例良性前列腺增生患者,根据手术方式分为HoLEP组(n=74)和TUPKP组(n=74)。比较两组患者围手术期相关指标、术前术后国际前列腺症状评分和生活质量评分。同时还对两组的术后并发症进行了统计:结果:HoLEP组的术中出血量、平均手术时间、导管留置时间和住院时间均低于TUPKP组(P < 0.001)。治疗前,两组的前列腺症状评分无明显差异(P > 0.05)。治疗后,HoLEP 组的前列腺症状评分明显低于 TUPKP 组(P < 0.001)。然而,术后HoLEP组的最大尿流率明显高于TUPKP组(P < 0.001),残余尿量明显低于TUPKP组(P < 0.001)。TUPKP组的并发症发生率为25.66%,明显高于HoLEP组的9.46%(P < 0.05)。HoLEP组的生活质量评分高于TUPKP组(P < 0.001):HoLEP治疗良性前列腺增生症有效、安全,术后并发症发生率低。
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来源期刊
Archivos Espanoles De Urologia
Archivos Espanoles De Urologia UROLOGY & NEPHROLOGY-
CiteScore
0.90
自引率
0.00%
发文量
111
期刊介绍: Archivos Españoles de Urología published since 1944, is an international peer review, susbscription Journal on Urology with original and review articles on different subjets in Urology: oncology, endourology, laparoscopic, andrology, lithiasis, pediatrics , urodynamics,... Case Report are also admitted.
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