Does the management of patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) changes with advanced diagnostic workup beyond coronary angiography? Results from the "Evaluation of the clinical Profile, Investigations and Cardiac Imaging of the Patients with MINOCA (EPIC-MINOCA Study)".

Yogesh Chander, Bhanu Duggal, Shishir Soni
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Abstract

Background: Evaluation of the patients with MINOCA and identifying the underlying aetiology remains challenging. However, investigation in most patients remains limited to coronary angiography (CAG). The study aimed to assess the clinical profile, investigations and cardiac imaging of the patients with MINOCA and its outcomes.

Results: Out of 55 patients with MINOCA, CAG was normal in 16 (29.1%), while 39 (69.9%) had nonobstructive coronary artery disease. Of 55 patients, 34 had limited workup (Group 1) and only 21 had advanced workup (Group 2). In comparison to Group 1, Group 2 had a significantly higher association with the identification of possible underlying aetiology (16 vs. 4, p < 0.001) and a change in the management (10 vs. 3, p = 0.002).

Conclusion: Diagnostic workup in patients with MINOCA was limited to CAG in 61.8% of patients in this study. However, patients with advanced workup had a significantly higher association with the change in the treatment and identifying possible underlying aetiology in such patients.

对冠状动脉非阻塞性心肌梗死(MINOCA)患者的管理是否会随着冠状动脉造影以外的高级诊断工作而改变?评估 MINOCA 患者的临床概况、检查和心脏成像(EPIC-MINOCA 研究)"的结果。
背景:对 MINOCA 患者进行评估并确定潜在病因仍具有挑战性。然而,大多数患者的检查仍局限于冠状动脉造影术(CAG)。该研究旨在评估 MINOCA 患者的临床概况、检查和心脏成像及其结果:在 55 名 MINOCA 患者中,16 人(29.1%)的 CAG 正常,39 人(69.9%)患有非阻塞性冠状动脉疾病。在 55 名患者中,34 人接受了有限的检查(第 1 组),只有 21 人接受了高级检查(第 2 组)。与第 1 组相比,第 2 组在发现可能的潜在病因方面的相关性明显更高(16 对 4,P 结论:第 2 组患者的诊断工作与第 1 组的相关性更高):在本研究中,61.8% 的 MINOCA 患者的诊断检查仅限于 CAG。然而,高级检查与改变治疗方法和确定可能的潜在病因的相关性明显更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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