Effect of physical activity on free fatty acids, insulin resistance, and blood pressure in obese older women.

Physical activity and nutrition Pub Date : 2024-06-01 Epub Date: 2024-06-30 DOI:10.20463/pan.2024.0009
Woo-Hyeon Son, Min-Seong Ha, Tae-Jin Park
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Abstract

Purpose: Obesity is characterized by a progressive increase in body fat accompanied by insulin resistance (IR) and elevated blood pressure (BP), and presents significant health risks, particularly in aged individuals. This study aimed to evaluate the effects of physical activity (PA) on free fatty acid (FFA) levels, IR, and BP in obese older women.

Methods: Twenty-three participants were randomly assigned to either the control group (CON, n = 11) or the physical activity group (PA, n = 12). The PA group was provided with a target of achieving >7,000 steps/day for 5 days each week. Body composition, FFA levels, IR, and BP were measured at pre- and post- of the 12-week intervention.

Results: The analysis revealed a statistically significant interaction between FFA (p < 0.01), IR (p < 0.01), and SBP (p < 0.001). FFA (p < 0.5), IR (p < 0.5), and systolic blood pressure (SBP) (p < 0.01) were significantly decreased in the PA group compared to those in the CON group, which showed no significant changes in FFA, IR, and SBP.

Conclusion: PA significantly decreased FFA, IR, and SBP in older women with obesity. Therefore, PA is an effective intervention for the prevention and management of obesity and cardiovascular diseases in obese older women.

体育锻炼对肥胖老年妇女体内游离脂肪酸、胰岛素抵抗和血压的影响。
目的:肥胖症的特点是身体脂肪逐渐增加,同时伴有胰岛素抵抗(IR)和血压升高(BP),对健康构成重大风险,尤其是对老年人而言。本研究旨在评估体力活动(PA)对肥胖老年妇女体内游离脂肪酸(FFA)水平、胰岛素抵抗和血压的影响:23名参与者被随机分配到对照组(CON,n = 11)或体育锻炼组(PA,n = 12)。PA组的目标是每周5天,每天走7000步。在为期 12 周的干预前后测量了身体成分、FFA 水平、IR 和血压:分析显示,FFA(p <0.01)、IR(p <0.01)和 SBP(p <0.001)之间存在统计学意义上的显著交互作用。与 CON 组相比,PA 组的 FFA(p < 0.5)、IR(p < 0.5)和收缩压(SBP)(p < 0.01)显著降低,而 CON 组的 FFA、IR 和 SBP 无显著变化:结论:PA 能明显降低肥胖老年妇女的 FFA、IR 和 SBP。因此,PA 是预防和控制老年肥胖妇女肥胖和心血管疾病的有效干预措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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