Not just tachycardia: A pilot study examining wound‑healing complications associated with the dose and volume of lignocaine in skin cancer excisions.

IF 1.6 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Australian Journal of General Practice Pub Date : 2024-08-01 DOI:10.31128/AJGP-04-23-6816

Joshua Eaton, Jessica Feeney, Tori Dopheide, Jessica Beattie, Rizwan Jaipurwala, Lara Fuller, Leesa Walker

{"title":"Not just tachycardia: A pilot study examining wound‑healing complications associated with the dose and volume of lignocaine in skin cancer excisions.","authors":"Joshua Eaton, Jessica Feeney, Tori Dopheide, Jessica Beattie, Rizwan Jaipurwala, Lara Fuller, Leesa Walker","doi":"10.31128/AJGP-04-23-6816","DOIUrl":null,"url":null,"abstract":"Background and objectives: General practitioners excise many suspected skin cancers using local anaesthetics such as lignocaine, but the relationships between the dose and volume of the local anaesthetic and wound complications are unclear. This pilot study considers an association between the dose and volume and complications.Method: An audit was conducted of patient records from two time periods: one before and one after an education intervention. Data extracted included lignocaine (volume and dose), wound complications (dehiscence and infection) and the demographics of patients and clinicians.Results: Both the dose and volume of lignocaine administered were significantly associated with complication rates (P=0.0084 and P=0.0209, respectively). In the post-intervention period, clinician behaviour changed, with a reduction in the volume and dose of lignocaine administered (P<0.001 and P<0.001, respectively) without episodes of inadequate analgesia.Discussion: This pilot study reported a relationship between lidocaine dose and volume and rates of complications. Shortcomings of this study limit attribution of findings to clinical practice. However, the results justify further rigorous research.","PeriodicalId":54241,"journal":{"name":"Australian Journal of General Practice","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Australian Journal of General Practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.31128/AJGP-04-23-6816","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Background and objectives: General practitioners excise many suspected skin cancers using local anaesthetics such as lignocaine, but the relationships between the dose and volume of the local anaesthetic and wound complications are unclear. This pilot study considers an association between the dose and volume and complications.

Method: An audit was conducted of patient records from two time periods: one before and one after an education intervention. Data extracted included lignocaine (volume and dose), wound complications (dehiscence and infection) and the demographics of patients and clinicians.

Results: Both the dose and volume of lignocaine administered were significantly associated with complication rates (P=0.0084 and P=0.0209, respectively). In the post-intervention period, clinician behaviour changed, with a reduction in the volume and dose of lignocaine administered (P<0.001 and P<0.001, respectively) without episodes of inadequate analgesia.

Discussion: This pilot study reported a relationship between lidocaine dose and volume and rates of complications. Shortcomings of this study limit attribution of findings to clinical practice. However, the results justify further rigorous research.

查看原文本刊更多论文

不仅仅是心动过速一项试点研究，探讨皮肤癌切除术中木质素卡因的剂量和用量与伤口愈合并发症的关系。

背景和目的：全科医生使用木质素等局部麻醉剂切除许多疑似皮肤癌，但局部麻醉剂的剂量和用量与伤口并发症之间的关系尚不清楚。本试验研究考虑了剂量和用量与并发症之间的关系：方法：对两个时间段的患者记录进行审核：一个是教育干预之前，另一个是教育干预之后。提取的数据包括木质素（用量和剂量）、伤口并发症（开裂和感染）以及患者和临床医生的人口统计学特征：结果：木质素卡因的剂量和用量与并发症发生率有明显相关性（P=0.0084 和 P=0.0209）。在干预后阶段，临床医生的行为发生了变化，木质碱的用量和剂量都有所减少（PD 讨论：这项试验研究报告了眼睑与眼睑之间的关系：这项试点研究报告了利多卡因剂量和用量与并发症发生率之间的关系。这项研究的不足之处限制了研究结果在临床实践中的应用。不过，这些结果证明有必要进行进一步的严格研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Australian Journal of General Practice Medicine-Family Practice

CiteScore

2.80

自引率

4.50%

发文量

284

期刊介绍： The Australian Journal of General Practice (AJGP) aims to provide relevant, evidence-based, clearly articulated information to Australian general practitioners (GPs) to assist them in providing the highest quality patient care, applicable to the varied geographic and social contexts in which GPs work and to all GP roles as clinician, researcher, educator, practice team member and opinion leader. All articles are subject to peer review before they are accepted for publication.