Relationship between 25-Hydroxyvitamin D3 Levels with Pain Intensity and Duration of Labor Stages in Primiparous Women.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-07-02 eCollection Date: 2024-05-01 DOI:10.4103/ijnmr.ijnmr_242_22

Mahsa Naderi Beni, Parvaneh Mousavi, Seyed Mahmood Latifi, Marjan Beigi, Zahra Abbaspoor

{"title":"Relationship between 25-Hydroxyvitamin D3 Levels with Pain Intensity and Duration of Labor Stages in Primiparous Women.","authors":"Mahsa Naderi Beni, Parvaneh Mousavi, Seyed Mahmood Latifi, Marjan Beigi, Zahra Abbaspoor","doi":"10.4103/ijnmr.ijnmr_242_22","DOIUrl":null,"url":null,"abstract":"Background: Prolonged labor is associated with various maternal and neonatal complications. This study aims to investigate the relationship between 25-hydroxyvitamin D3 levels and pain intensity and duration of labor stages in primiparous women.Materials and methods: This cross-sectional study was conducted in Iran from November 2021 to January 2022 and comprised primiparous women who were in active labor after a term pregnancy (37-42 weeks). Five milliliter of blood was taken from each subject and centrifuged for the measurement of vitamin D level using the enzyme-linked immunosorbent assay method. The High-Performance Liquid Chromatography (HLPC) method was used to measure 25-OH vitamin D. In addition, through history, examination, and investigations, the subjects were evaluated according to the pain intensity and duration of the first (active phase) and second stages of labor.Results: The results of the Pearson correlation test indicated a significant relationship between vitamin D and active phase duration (r = 0.64, p = 0.012), second stage duration (r = 0.73, p = 0.001), pain intensity of the active phase (r = 0.61, p = 0.022), and pain intensity of the second stage (r = 0.65, p = 0.026). According to the analysis of variance table, based on vitamin D, there were statistically significant differences between the groups in terms of the active phase duration, second stage duration, pain intensity of the active phase, and that of the second stage of labor (p < 0.05).Conclusions: Low levels of vitamin D may influence the progress of labor and increase the rate of prolonged labor.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11296596/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ijnmr.ijnmr_242_22","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/5/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Prolonged labor is associated with various maternal and neonatal complications. This study aims to investigate the relationship between 25-hydroxyvitamin D3 levels and pain intensity and duration of labor stages in primiparous women.

Materials and methods: This cross-sectional study was conducted in Iran from November 2021 to January 2022 and comprised primiparous women who were in active labor after a term pregnancy (37-42 weeks). Five milliliter of blood was taken from each subject and centrifuged for the measurement of vitamin D level using the enzyme-linked immunosorbent assay method. The High-Performance Liquid Chromatography (HLPC) method was used to measure 25-OH vitamin D. In addition, through history, examination, and investigations, the subjects were evaluated according to the pain intensity and duration of the first (active phase) and second stages of labor.

Results: The results of the Pearson correlation test indicated a significant relationship between vitamin D and active phase duration (r = 0.64, p = 0.012), second stage duration (r = 0.73, p = 0.001), pain intensity of the active phase (r = 0.61, p = 0.022), and pain intensity of the second stage (r = 0.65, p = 0.026). According to the analysis of variance table, based on vitamin D, there were statistically significant differences between the groups in terms of the active phase duration, second stage duration, pain intensity of the active phase, and that of the second stage of labor (p < 0.05).

Conclusions: Low levels of vitamin D may influence the progress of labor and increase the rate of prolonged labor.

查看原文本刊更多论文

初产妇 25-羟维生素 D3 水平与疼痛强度和产程持续时间的关系

背景：产程延长与产妇和新生儿的各种并发症有关。本研究旨在调查初产妇 25- 羟维生素 D3 水平与疼痛强度和产程持续时间之间的关系：这项横断面研究于 2021 年 11 月至 2022 年 1 月在伊朗进行，研究对象包括足月妊娠（37-42 周）后处于活跃产程的初产妇。每位受试者抽取 5 毫升血液，离心后使用酶联免疫吸附法测定维生素 D 水平。采用高效液相色谱法（HLPC）测量 25-OH 维生素 D。此外，通过病史、检查和化验，根据第一产程（活跃期）和第二产程的疼痛强度和持续时间对受试者进行评估：皮尔逊相关检验结果表明，维生素 D 与活跃期持续时间（r = 0.64，p = 0.012）、第二产程持续时间（r = 0.73，p = 0.001）、活跃期疼痛强度（r = 0.61，p = 0.022）和第二产程疼痛强度（r = 0.65，p = 0.026）之间存在显著关系。根据方差分析表，以维生素 D 为基础，各组间在活跃期持续时间、第二产程持续时间、活跃期疼痛强度和第二产程疼痛强度方面存在显著统计学差异（P < 0.05）：结论：维生素 D 水平过低可能会影响产程进展并增加产程延长率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.