Global prevalence of diet low in calcium and the disease burden: results from the Global Burden of Disease Study 2019.

IF 4.6 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Gang Ti, Yuan He, Youde Xiao, Jiyuan Yan, Rong Ding, Pengfei Cheng, Wei Wu, Dawei Ye, Jinxi Wang, Lili Li
{"title":"Global prevalence of diet low in calcium and the disease burden: results from the Global Burden of Disease Study 2019.","authors":"Gang Ti, Yuan He, Youde Xiao, Jiyuan Yan, Rong Ding, Pengfei Cheng, Wei Wu, Dawei Ye, Jinxi Wang, Lili Li","doi":"10.1038/s41387-024-00321-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Due to the essential role of calcium in vital biological functions, diet low in calcium (DLC) is associated with various diseases. However, there is a lack of study about the current prevalence and health burden due to DLC using reliable data sources.</p><p><strong>Methods: </strong>We used data from the Global Burden of Disease study 2019 (GBD 2019) to estimate the prevalence and health burden of DLC in 204 countries from 1990 to 2019, by age, sex, and sociodemographic index (SDI). The estimates were produced in DisMod-MR 2.1, a Bayesian meta-regression tool. Summary exposure value (SEV) was used to show the prevalence of DLC, while diseases adjusted life year (DALY) was used to represent the disease burden. The disease burden was estimated for DLC-induced colorectal cancer. Spearman Rank Order correlation was used for correlation analysis, and estimated annual percentage (EAPC) was used to reflect the temporal trends.</p><p><strong>Results: </strong>From 1990 to 2019, the global prevalence of DLC decreased (EAPC of SEV, -0.47; 95% CI, -0.5 to -0.43), but have increased in Oceania region and in many countries, such as United Arab Emirates, New Zealand, Japan, and France. The global DALYs associated with low in calcium were estimated to be 3.14 million (95% uncertainty interval (UI), 2.25-4.26 million) in 2019, with an age standardized rate of 38.2 (95% UI, 27.2-51.8) per 100,000. Unlike the prevalence, the global age standardized DALY rates has remained unchanged (EAPC, -0.03; 95% CI, -0.12 to 0.07), but has increased in over 80 of the 204 countries, located mainly in Asia, Africa, and South America. In all years and regions, the age standardized SEV and DALY rates were higher in male people than that in female people. The prevalence (rho = -0.823; P < 0.001) and disease burden (rho = -0.433; P < 0.001) associated with diet in low calcium were strongly correlated to SDI. The prevalence decreased with age, but the DALY rates increased with age and peaked at about 90 years. The prevalence of DLC has decreased worldwide and in most countries, but the disease burden of DLC induced colorectal cancer has increased in over 40% of countries worldwide.</p><p><strong>Conclusion: </strong>Countries with low sociodemographic level and male people are more likely to experience the risk of DLC and related disease burden. Related measures in improve dietary calcium intake are in need to address diet in low calcium related health problems.</p>","PeriodicalId":19339,"journal":{"name":"Nutrition & Diabetes","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11297965/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition & Diabetes","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41387-024-00321-2","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Due to the essential role of calcium in vital biological functions, diet low in calcium (DLC) is associated with various diseases. However, there is a lack of study about the current prevalence and health burden due to DLC using reliable data sources.

Methods: We used data from the Global Burden of Disease study 2019 (GBD 2019) to estimate the prevalence and health burden of DLC in 204 countries from 1990 to 2019, by age, sex, and sociodemographic index (SDI). The estimates were produced in DisMod-MR 2.1, a Bayesian meta-regression tool. Summary exposure value (SEV) was used to show the prevalence of DLC, while diseases adjusted life year (DALY) was used to represent the disease burden. The disease burden was estimated for DLC-induced colorectal cancer. Spearman Rank Order correlation was used for correlation analysis, and estimated annual percentage (EAPC) was used to reflect the temporal trends.

Results: From 1990 to 2019, the global prevalence of DLC decreased (EAPC of SEV, -0.47; 95% CI, -0.5 to -0.43), but have increased in Oceania region and in many countries, such as United Arab Emirates, New Zealand, Japan, and France. The global DALYs associated with low in calcium were estimated to be 3.14 million (95% uncertainty interval (UI), 2.25-4.26 million) in 2019, with an age standardized rate of 38.2 (95% UI, 27.2-51.8) per 100,000. Unlike the prevalence, the global age standardized DALY rates has remained unchanged (EAPC, -0.03; 95% CI, -0.12 to 0.07), but has increased in over 80 of the 204 countries, located mainly in Asia, Africa, and South America. In all years and regions, the age standardized SEV and DALY rates were higher in male people than that in female people. The prevalence (rho = -0.823; P < 0.001) and disease burden (rho = -0.433; P < 0.001) associated with diet in low calcium were strongly correlated to SDI. The prevalence decreased with age, but the DALY rates increased with age and peaked at about 90 years. The prevalence of DLC has decreased worldwide and in most countries, but the disease burden of DLC induced colorectal cancer has increased in over 40% of countries worldwide.

Conclusion: Countries with low sociodemographic level and male people are more likely to experience the risk of DLC and related disease burden. Related measures in improve dietary calcium intake are in need to address diet in low calcium related health problems.

Abstract Image

全球低钙饮食流行率与疾病负担:2019 年全球疾病负担研究结果。
背景:由于钙在重要的生物功能中起着至关重要的作用,低钙饮食(DLC)与各种疾病相关。然而,目前缺乏利用可靠数据来源对低钙饮食的流行率和健康负担的研究:我们利用 2019 年全球疾病负担研究(GBD 2019)的数据,按年龄、性别和社会人口指数(SDI)估算了 1990 年至 2019 年期间 204 个国家的 DLC 患病率和健康负担。估算结果由贝叶斯元回归工具 DisMod-MR 2.1 生成。摘要暴露值(SEV)用于显示 DLC 的患病率,疾病调整生命年(DALY)用于表示疾病负担。对 DLC 引发的结直肠癌的疾病负担进行了估算。相关性分析采用斯皮尔曼等级相关性(Spearman Rank Order correlation),估计年百分比(EAPC)用于反映时间趋势:从 1990 年到 2019 年,DLC 的全球患病率有所下降(SEV 的 EAPC,-0.47;95% CI,-0.5 至 -0.43),但大洋洲地区和许多国家(如阿拉伯联合酋长国、新西兰、日本和法国)的患病率有所上升。据估计,2019 年全球与低钙有关的残疾调整寿命年数为 314 万(95% 不确定区间(UI),225 万-426 万),年龄标准化比率为每 10 万人 38.2(95% UI,27.2-51.8)。与患病率不同,全球年龄标准化残疾调整寿命年数率保持不变(EAPC,-0.03;95% CI,-0.12 至 0.07),但在 204 个国家中,有 80 多个国家的年龄标准化残疾调整寿命年数率有所上升,这些国家主要位于亚洲、非洲和南美洲。在所有年份和地区,男性的年龄标准化 SEV 和 DALY 率均高于女性。发病率(rho = -0.823;P 结论:男性发病率高于女性:社会人口水平较低的国家和男性更有可能面临 DLC 风险和相关疾病负担。需要采取相关措施提高膳食中钙的摄入量,以解决膳食中与低钙相关的健康问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Nutrition & Diabetes
Nutrition & Diabetes ENDOCRINOLOGY & METABOLISM-NUTRITION & DIETETICS
CiteScore
9.20
自引率
0.00%
发文量
50
审稿时长
>12 weeks
期刊介绍: Nutrition & Diabetes is a peer-reviewed, online, open access journal bringing to the fore outstanding research in the areas of nutrition and chronic disease, including diabetes, from the molecular to the population level.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信