Characteristics of sialolithiasis in Israel, a big-data retrospective study of 5100 cases.

IF 2.9 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-08-04 DOI:10.1111/odi.15095

Ehud Jonas, Daniel Muchnik, Idan Rabinovich, Daya Masri, Gavriel Chaushu, Gal Avishai

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引用次数: 0

Abstract

Objective: The aim of this study was to identify risk factors for sialolithiasis patients using a large community and hospital-based cohort.

Methods: A retrospective case-control study was conducted on 20,396 individuals, including 5100 sialolithiasis patients and 15,296 matched controls. Demographics and laboratory data were obtained from electronic medical records. Statistical analyses were performed to identify significant differences between the two groups. A p-value of <0.05 was considered significant.

Results: Sialolithiasis was more prevalent in women, with a mean age at diagnosis of 55.75 years. Several geographic location variables emerged as risk factors for sialolithiasis including Israeli birth, higher socioeconomic communities, and specific areas of residency. Tobacco smoking (odds ratio = 1.46) was a significant risk factor. Low high-density lipoprotein levels, elevated triglycerides, and elevated amylase levels were associated with sialolithiasis.

Conclusions: This study provides valuable insights into the demographic and laboratory characteristics of sialolithiasis patients, indicating that area of residency and lifestyle factors contribute to the risk of developing sialolithiasis. The findings may contribute to a better understanding of the disease and the development of preventative measures or early diagnostics tools.

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以色列霰粒肿的特点，5100 例病例的大数据回顾性研究。

研究目的本研究的目的是通过一个大型社区和医院队列来确定胆石症患者的风险因素：方法：对 20,396 人进行了回顾性病例对照研究，其中包括 5100 名霰粒肿患者和 15,296 名匹配对照者。人口统计学和实验室数据来自电子病历。研究进行了统计分析，以确定两组间的显著差异。结果显示，P 值为霰粒肿在女性中发病率较高，确诊时的平均年龄为 55.75 岁。一些地理位置变量成为矽结石的风险因素，包括以色列人出生、社会经济地位较高的社区和特定的居住地区。吸烟（几率比=1.46）是一个重要的风险因素。高密度脂蛋白水平低、甘油三酯升高和淀粉酶水平升高与胆石症有关：这项研究为了解胆石症患者的人口统计学和实验室特征提供了宝贵的信息，表明居住地区和生活方式因素是胆石症发病风险的重要因素。研究结果可能有助于更好地了解该疾病，并开发预防措施或早期诊断工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral diseases 医学-牙科与口腔外科

CiteScore

7.60

自引率

5.30%

发文量

325

审稿时长

4-8 weeks

期刊介绍： Oral Diseases is a multidisciplinary and international journal with a focus on head and neck disorders, edited by leaders in the field, Professor Giovanni Lodi (Editor-in-Chief, Milan, Italy), Professor Stefano Petti (Deputy Editor, Rome, Italy) and Associate Professor Gulshan Sunavala-Dossabhoy (Deputy Editor, Shreveport, LA, USA). The journal is pre-eminent in oral medicine. Oral Diseases specifically strives to link often-isolated areas of dentistry and medicine through broad-based scholarship that includes well-designed and controlled clinical research, analytical epidemiology, and the translation of basic science in pre-clinical studies. The journal typically publishes articles relevant to many related medical specialties including especially dermatology, gastroenterology, hematology, immunology, infectious diseases, neuropsychiatry, oncology and otolaryngology. The essential requirement is that all submitted research is hypothesis-driven, with significant positive and negative results both welcomed. Equal publication emphasis is placed on etiology, pathogenesis, diagnosis, prevention and treatment.