[Hepatitis C: From diagnosis to global virus elimination].

Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-08-01 Epub Date: 2024-08-02 DOI:10.1055/a-2057-1797
Annika Schmitt, Christoph Sarrazin
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引用次数: 0

Abstract

Chronic infection with hepatitis C virus (HCV) is a common cause of complications such as liver cirrhosis and hepatocellular carcinoma (HCC). It is one of the most significant infectious diseases worldwide, posing a substantial health burden. Since the introduction of direct-acting antiviral agents (DAAs), the treatment landscape has undergone a revolution. HCV infection is curable, and the treatment is safe and well tolerated. Due to the availability of this effective therapeutic option, the World Health Organization (WHO) set an ambitious goal in 2015 to eliminate Hepatitis C by 2030, a goal that the German government also embraced in 2016. The key tasks involve identifying previously undiagnosed cases and ensuring they receive antiviral treatment. Addressing at-risk populations through specific measures, including micro-elimination projects and population-wide campaigns, is essential to achieving the WHO's target both in Germany and globally.

[丙型肝炎:从诊断到全球消除病毒]。
丙型肝炎病毒(HCV)慢性感染是导致肝硬化和肝细胞癌(HCC)等并发症的常见原因。它是全球最重要的传染病之一,造成了巨大的健康负担。自直接作用抗病毒药物(DAAs)问世以来,治疗领域经历了一场革命。HCV感染是可以治愈的,而且治疗安全、耐受性好。由于有了这种有效的治疗方法,世界卫生组织(WHO)于 2015 年制定了到 2030 年消除丙型肝炎的宏伟目标,德国政府也于 2016 年接受了这一目标。主要任务包括发现以前未确诊的病例,并确保他们接受抗病毒治疗。要在德国和全球实现世卫组织的目标,必须通过具体措施(包括微观消除项目和全民运动)解决高危人群的问题。
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