The impact of peri-procedural imaging on safety and efficacy of atrial fibrillation ablation: insights from the Israeli AF Catheter Ablation Registry (ICAR).

IF 2.1 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Ibrahim Marai, Adi Elias, Guy Rozen, Roy Beinart, Eyal Nof, Yoav Michowitz, Michael Glikson, Yuval Konstantino, Moti Haim, David Luria, Alexander Omelchenko, Avishag Laish-Farkash, Mahmoud Suleiman
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引用次数: 0

Abstract

Background: Pulmonary vein isolation (PVI) is the most effective therapy to achieve rhythm control in atrial fibrillation (AF). Peri-procedural imaging is used in many but not all centers. However, the impact of imaging on safety and efficacy of PVI is not clear. The Israeli Catheter Ablation Registry (ICAR) is a great opportunity to explore this issue in real-world practice.

Aim: To describe the real-world utilization of peri-procedural imaging technologies in a large cohort of patients undergoing ablation for AF.

Methods: A prospective-multicenter cohort of AF patients who underwent PVI during the years 2019-2021. Peri-procedural imaging (CT, ICE, TEE) was utilized based on the center and operator discretion. The study endpoints were peri-procedural complications and AF recurrence at 12 months follow-up among patients with and without peri-procedural imaging.

Results: Between January 2019 and December 2021, a total of 921 patients underwent PVI. Peri-procedural imaging (at least 1 modality of CT, TEE, and or ICE) was utilized in 753 (81.8%) and no imaging among 168 (18.2%) patients. Cryoablation was the dominant energy used for PVI in both groups (92.3% of the non-imaging group, and 95.3% among imaging group), while RF was used in the rest of the patients. Fluoroscopy time was not different between the 2 groups; however, procedure duration was longer among the imaging group (90 min) compared to the non-imaging group (74.5 min, p = 0.006). By 12 months, the incidence of AF recurrence and repeated ablation were not different between the groups. Complications and re-hospitalization for cardiocerebrovascular reasons were not different among the 2 groups. Cox regression model demonstrated no association between preprocedural imaging and the risk of AF recurrence after ablation.

Conclusion: This real-world multicenter prospective registry study demonstrated that the rate of complications and the rate of recurrence of AF during 1 year follow-up were not different among patients who had PVI either with or without peri-procedural imaging.

Abstract Image

围手术期成像对心房颤动消融安全性和有效性的影响:以色列心房颤动导管消融注册中心 (ICAR) 的见解。
背景:肺静脉隔离术(PVI)是实现房颤节律控制的最有效疗法。许多中心都采用了手术前成像,但并非所有中心都这样做。然而,成像对 PVI 安全性和有效性的影响尚不明确。以色列导管消融注册中心(ICAR)为我们提供了一个在真实世界中探索这一问题的绝佳机会。目的:描述一大批接受房颤消融术的患者在真实世界中使用围手术期成像技术的情况:2019-2021年间接受PVI的房颤患者的前瞻性多中心队列。根据中心和操作者的决定使用术前成像(CT、ICE、TEE)。研究终点是接受和未接受围手术期成像的患者在随访12个月时的围手术期并发症和房颤复发情况:2019年1月至2021年12月期间,共有921名患者接受了PVI手术。753例(81.8%)患者进行了术前成像(至少一种 CT、TEE 和 ICE),168 例(18.2%)患者未进行成像。在两组患者中,冷冻消融都是 PVI 的主要能量来源(在无造影组中占 92.3%,在造影组中占 95.3%),其余患者则使用射频。两组患者的透视时间没有差异;但成像组的手术时间(90 分钟)长于非成像组(74.5 分钟,P = 0.006)。12 个月后,两组房颤复发和重复消融的发生率没有差异。并发症和因心脑血管原因再次住院的情况在两组之间没有差异。Cox回归模型显示,术前成像与消融术后房颤复发风险之间没有关联:这项真实世界的多中心前瞻性登记研究表明,在随访1年期间,进行PVI术前成像或未进行术前成像的患者的并发症发生率和房颤复发率没有差异。
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来源期刊
CiteScore
4.30
自引率
11.10%
发文量
320
审稿时长
4-8 weeks
期刊介绍: The Journal of Interventional Cardiac Electrophysiology is an international publication devoted to fostering research in and development of interventional techniques and therapies for the management of cardiac arrhythmias. It is designed primarily to present original research studies and scholarly scientific reviews of basic and applied science and clinical research in this field. The Journal will adopt a multidisciplinary approach to link physical, experimental, and clinical sciences as applied to the development of and practice in interventional electrophysiology. The Journal will examine techniques ranging from molecular, chemical and pharmacologic therapies to device and ablation technology. Accordingly, original research in clinical, epidemiologic and basic science arenas will be considered for publication. Applied engineering or physical science studies pertaining to interventional electrophysiology will be encouraged. The Journal is committed to providing comprehensive and detailed treatment of major interventional therapies and innovative techniques in a structured and clinically relevant manner. It is directed at clinical practitioners and investigators in the rapidly growing field of interventional electrophysiology. The editorial staff and board reflect this bias and include noted international experts in this area with a wealth of expertise in basic and clinical investigation. Peer review of all submissions, conflict of interest guidelines and periodic editorial board review of all Journal policies have been established.
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