A new isocoumarin derivative from endophytic fungus Pezicula neosporulosa VDB39 from Vaccinium dunalianum.

IF 1.3 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2024-08-02 DOI:10.1080/10286020.2024.2385367

Yuan-Cao Shu, Zhi-Yu Zhang, Xiao-Man Fu, Wei-Lin Zeng, Guo-Lei Zhu, Xiao-Qin Yang, Si-Da Xie, Wei-Hua Wang, Ping Zhao

引用次数: 0

Abstract

Four isocoumarin derivatives (1-4) and five phenols (5-9) were obtained from the endophytic fungus Pezicula neosporulosa VDB39, which was isolated from the branches of Vaccinium dunalianum Wight (Ericaceae). Compound 1 is a new derivative of isocoumarin. The structures were elucidated by spectroscopic methods. Single X-ray crystallography confirmed the absolute configuration of compound 1. Additionally, the antiphytopathogenic fungi activity of isocoumarin derivatives (1-4) was evaluated.

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一种新的异香豆素衍生物，来自于越橘内生真菌新孢子瘤 Pezicula neosporulosa VDB39。

从内生真菌 Pezicula neosporulosa VDB39 中获得了四种异香豆素衍生物（1-4）和五种酚类化合物（5-9）。化合物 1 是异香豆素的一种新衍生物。通过光谱方法阐明了其结构。此外，还评估了异香豆素衍生物（1-4）的抗致病真菌活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.