Sleep Characteristics, Magnetic Resonance Imaging- and Dual-Energy X-Ray Absorptiometry-Based Morphological Parameters, Muscle Strength, and Risk of Falls in Sedentary Older Subjects.

IF 1.4 4区 医学 Q4 GERIATRICS & GERONTOLOGY
Stefano Borghi, Antonio La Torre, Carmelo Messina, Luca M Sconfienza, Giuseppe Banfi, Jacopo A Vitale
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引用次数: 0

Abstract

Background: The aims of this cross-sectional study were to (a) assess actigraphy-based sleep parameters (total sample and gender differences), (b) assess differences in morphological parameters and physical function between short- versus normal-sleepers and poor- versus good-sleepers, and (c) assess the possible correlations between sleep variables and morphological and physical function parameters in older subjects.

Methods: This study enrolled 42 healthy older participants (60-80 years). Participants completed the following clinical evaluations: (1) whole-body dual-energy X-ray absorptiometry to assess the appendicular skeletal muscle mass index; (2) magnetic resonance imaging acquisition to determine the cross-sectional muscle area of thigh muscles and intermuscular adipose tissue; (3) risk of fall assessment through the mini-Balance Evaluation Systems Test; (4) strength assessment: (a) chair stand test and (b) handgrip strength test; (5) sleep monitoring by actigraphy to assess total sleep time, sleep efficiency, wake after sleep onset, sleep latency, fragmentation index, mobile time, and subjective sleep quality.

Results: 31.0% of subjects were short-sleepers (total sleep time < 6 hr), 19.1% were poor-sleepers (sleep efficiency < 85%), and gender differences were detected in mobile time (males: 15.8 ± 6.0 and females: 13.4 ± 6.8; p < .001) and fragmentation index (males: 35.3 ± 14.3 and females: 29.6 ± 14.6; p < .001); no significant differences were observed between groups (short- vs. normal-sleepers and poor- vs. good-sleepers) in morphological and physical function variables; correlation analysis showed that sleep latency negatively correlated with Mini-Balance Evaluation Systems Test (r = -.352; p = .022) and a positive correlation was detected between cross-sectional muscle area and mobile time (r = .349, p = .023).

Conclusion: No differences were observed in morphological and function parameters between good- versus poor-sleepers, those subjects with worse sleep onset latency (i.e., longer time to fall asleep) registered higher for risk of fall. The potential role of sleep in the physiological mechanisms of muscular aging must be explored through cross-sectional cohort studies with a larger population.

久坐老年人的睡眠特征、基于磁共振成像和双能量 X 射线吸收测量的形态参数、肌肉力量和跌倒风险。
研究背景这项横断面研究的目的是:(a) 评估基于动图的睡眠参数(样本总数和性别差异);(b) 评估短时睡眠者与正常睡眠者、睡眠差者与睡眠好者在形态参数和身体功能方面的差异;(c) 评估老年受试者的睡眠变量与形态参数和身体功能参数之间可能存在的相关性:本研究共招募了 42 名健康的老年人(60-80 岁)。参与者完成了以下临床评估:(1) 全身双能 X 射线吸收测量,以评估阑尾骨骼肌质量指数;(2) 磁共振成像采集,以确定大腿肌肉和肌间脂肪组织的横截面积;(3) 通过小型平衡评估系统测试进行跌倒风险评估;(4) 力量评估:(a) 椅子站立测试和 (b) 手握力测试;(5) 通过行为监测仪进行睡眠监测,以评估总睡眠时间、睡眠效率、睡眠开始后的唤醒情况、睡眠潜伏期、破碎指数、移动时间和主观睡眠质量。结果显示31.0%的受试者睡眠时间短(总睡眠时间小于 6 小时),19.1%的受试者睡眠质量差(睡眠效率小于 85%),移动时间(男性:15.8 ± 6.0,女性:13.4 ± 6.8;p < .001)和破碎指数(男性:35.3 ± 14.3,女性:29.6 ± 14.6;p < .001)存在性别差异。相关分析表明,睡眠潜伏期与迷你平衡评估系统测试呈负相关(r = -.352;p = .022),横截面肌肉面积与移动时间呈正相关(r = .349,p = .023):结论:睡眠好与睡眠差的人在形态和功能参数上没有差异,但睡眠起始潜伏期较差(即入睡时间较长)的人发生跌倒的风险较高。睡眠在肌肉老化的生理机制中的潜在作用必须通过更多人群的横断面队列研究来探索。
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来源期刊
CiteScore
2.60
自引率
6.70%
发文量
105
审稿时长
>12 weeks
期刊介绍: The Journal of Aging and Physical Activity (JAPA) is a multidisciplinary journal that publishes peer-reviewed original research reports, scholarly reviews, and professional-application articles on the relationship between physical activity and the aging process. The journal encourages the submission of articles that can contribute to an understanding of (a) the impact of physical activity on physiological, psychological, and social aspects of older adults and (b) the effect of advancing age or the aging process on physical activity among older adults. In addition to publishing research reports and reviews, JAPA publishes articles that examine the development, implementation, and evaluation of physical activity programs among older adults. Articles from the biological, behavioral, and social sciences, as well as from fields such as medicine, clinical psychology, physical and recreational therapy, health, physical education, and recreation, are appropriate for the journal. Studies using animal models do not fit within our mission statement and should be submitted elsewhere.
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