Spontaneous bone regeneration in segmental mandibular defects: A systematic review.

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Medicina Oral Patologia Oral Y Cirugia Bucal Pub Date : 2024-11-01 DOI:10.4317/medoral.26712

T Wei, Y Fan, S Li, Y Cai, X Peng, P Ye

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引用次数: 0

Abstract

Background: Rehabilitation for segmental mandibular defect is vital for mastication function and facial aesthetics. Interestingly spontaneous bone regeneration after segmental mandibulectomy sporadically occurs to avoid further bony rehabilitation. This study aimed to assess the potential of spontaneous bone regeneration in the treatment of mandibular defects.

Material and methods: An electronic search was conducted using the PubMed, EMBASE, Wiley Online Library, and Cochrane Library databases to identify eligible studies. Critical appraisal of the included articles was done using the Joanna Briggs Institute critical appraisal checklist.

Results: A total of 35 studies, including 60 patients, that investigated spontaneous bone regeneration after segmental mandibulectomy were included. Among these patients, 39 (65%) were male and 21 (35%) were female, with a mean age of 20.81 ± 16.38 years. Periosteum was completely and partially preserved during mandibulectomy in 25 and 13 patients, respectively. Continuous bone regeneration between mandibular stumps was observed in 53 (88.3%) patients during follow-up. Although the mandibular stump was not stabilized in 13 (21.67%) patients, continuous bony regeneration still occurred, with a mean recovery period of 30.29 months. This was significantly greater than the overall average recovery time of 19.87 months.

Conclusions: Spontaneous bone regeneration could occur in segmental mandibular defects, particularly in young patients with intact periosteum and rigid mandibular stump fixation.

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下颌骨节段性缺损的自发性骨再生：系统综述。

背景：下颌骨节段性缺损的修复对咀嚼功能和面部美观至关重要。有趣的是，下颌骨节段切除术后会出现零星的自发性骨再生，以避免进一步的骨康复。本研究旨在评估自发性骨再生在下颌骨缺损治疗中的潜力：使用 PubMed、EMBASE、Wiley Online Library 和 Cochrane Library 数据库进行电子检索，以确定符合条件的研究。采用乔安娜-布里格斯研究所（Joanna Briggs Institute）的批判性评估清单对纳入的文章进行批判性评估：共纳入了 35 项研究，包括 60 名患者，这些研究调查了下颌骨节段切除术后的自发性骨再生情况。这些患者中有 39 名男性（65%）和 21 名女性（35%），平均年龄为 20.81±16.38 岁。分别有 25 名和 13 名患者在下颌骨切除术中完全和部分保留了骨膜。在随访期间，53 名（88.3%）患者的下颌骨残端之间出现了持续的骨再生。虽然有 13 例（21.67%）患者的下颌骨残端未得到稳定，但仍出现了持续的骨再生，平均恢复期为 30.29 个月。结论：自发性骨再生可在下颌骨残端和残端之间发生：结论：下颌骨节段性缺损可发生自发性骨再生，尤其是在骨膜完整、下颌骨残端固定严格的年轻患者中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medicina Oral Patologia Oral Y Cirugia Bucal DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

4.60

自引率

0.00%

发文量

审稿时长

3-8 weeks

期刊介绍： 1. Oral Medicine and Pathology: Clinicopathological as well as medical or surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, as well as orofacial neurological disorders, and systemic conditions with an impact on the oral cavity. 2. Oral Surgery: Surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, teeth, implants, oral surgical procedures. Surgical management of diseases affecting head and neck areas. 3. Medically compromised patients in Dentistry: Articles discussing medical problems in Odontology will also be included, with a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients. 4. Implantology 5. Periodontology