Numerical modeling and analysis of cardiac stent using blood hammer principle.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Seethalakshmi R, Hariharan S, Hemalatha Karnan, Keerthana V, Akshara V
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引用次数: 0

Abstract

Background: Atherosclerosis is a condition which disrupts blood flow due to plaque build-up inside the arteries. Under conditions where consecutive plaques are prevailing blood hammer principle is exhibited.

Objective: The pressure and shear stress produced at an infinitesimal area act as the governing equation for stent modeling. The leading order pressure lays the foundation for the design of cardiac stents with definite dimensions.

Method: The designed stent was encapsulated inside a crimper validated through ANSYS-static and transient structural simulation to derive the total deformation, equivalent strain, and stress exerted on the stent. Five different biomaterials stainless steel 316, cobalt, chromium, platinum, and Poly lactic acid were selected for the material assessment.

Result: Static and Transient structural analysis for a period of 1 and 10 secs was implemented for a stent with and without a crimper. The material performance in terms of total deformation, equivalent stress, and strain are analyzed.

Conclusion: The paper envisions the dynamics of blood hammer in atherosclerosis that provides the changes in the pressure and clotting process. It shows the promising results of the stent behavior in varied forces which gives valuable insights for future improvement in stent design and material selection.

利用血锤原理对心脏支架进行数值建模和分析。
背景:动脉粥样硬化是动脉内斑块堆积导致的血流障碍。在连续斑块盛行的情况下,会出现血锤原理:无穷小区域产生的压力和剪切应力是支架建模的控制方程。前阶压力为设计具有确定尺寸的心脏支架奠定了基础:方法:通过 ANSYS 静态和瞬态结构模拟验证将设计的支架封装在卷曲器中,从而得出支架的总变形、等效应变和应力。材料评估选择了五种不同的生物材料:不锈钢 316、钴、铬、铂和聚乳酸:结果:对带卷边器和不带卷边器的支架分别进行了 1 秒和 10 秒的静态和瞬态结构分析。结果:对带卷边器和不带卷边器的支架进行了 1 秒和 10 秒的静态和瞬态结构分析,分析了材料在总变形、等效应力和应变方面的性能:本文设想了动脉粥样硬化中血锤的动态变化,提供了压力和凝血过程的变化。它显示了支架在不同压力下的行为结果,为今后改进支架设计和材料选择提供了宝贵的见解。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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