RETRACTION: Nuclear Clusterin Accumulation during Heat Shock Response: Implications for Cell Survival and Thermo-tolerance Induction in Immortalized and Prostate Cancer Cells

IF 4.5 2区生物学 Q2 CELL BIOLOGY

Journal of Cellular Physiology Pub Date : 2024-08-02 DOI:10.1002/jcp.31374

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引用次数: 0

Abstract

RETRACTION: A. E. Caccamo, S. Desenzani, L. Belloni, A. F. Borghetti, S. Bettuzzi, “Nuclear Clusterin Accumulation during Heat Shock Response: Implications for Cell Survival and Thermo-tolerance Induction in Immortalized and Prostate Cancer Cells,” Journal of Cellular Physiology 207, no. 1 (2006): 208-219, https://doi.org/10.1002/jcp.20561.

The above article, published online on 5 December 2005 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Alexander Hutchison; and Wiley Periodicals LLC. The retraction has been agreed following allegations raised by third parties. Several lanes within the Western Blot images displayed in Figures 1 A, 2 A, 2B, and 7 were found to display highly similar patterns despite depicting protein extracts from samples of different origin/treatment. As the raw data could not be retrieved due to the significant time elapsed since publication, the concerns could not be addressed. In light of the significant number of concerns, the editors have lost trust in the overall accuracy of the data presented. The corresponding author S. Bettuzzi disagrees with the decision of retraction. Confirmation of retraction could not be obtained by the remaining co-authors.

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回放：热休克反应过程中的核簇蛋白积累：细胞存活和热耐受诱导对永生化细胞和前列腺癌细胞的影响

撤回：A. E. Caccamo, S. Desenzani, L. Belloni, A. F. Borghetti, S. Bettuzzi, "Nuclear Clusterin Accumulation during Heat Shock Response. Implications for Cell Survival and Thermo-tolerance Induction in Immortalized and Prostate Cancer Cells," Journal of Cellular Physology 207, no：细胞生理学杂志》第 207 卷第 1 期（2006 年），"Nuclear Clusterin Accumulation during Heat Shock Response: Implications for Cell Survival and Thermo-tolerance Induction in Immortalized and Prostate Cancer Cells," 208-219, ：208-219, https://doi.org/10.1002/jcp.20561.上述文章于 2005 年 12 月 5 日在线发表于 Wiley Online Library (wileyonlinelibrary.com)，经期刊主编 Alexander Hutchison 和 Wiley Periodicals LLC 协议撤回。撤稿是在第三方提出指控后达成的。在图 1 A、图 2 A、图 2 B 和图 7 中显示的 Western Blot 图像中，有几条泳道尽管描绘的是不同来源/处理的样本蛋白质提取物，但却显示出高度相似的模式。由于原始数据自发表以来已过去了很长时间，因此无法检索，也就无法解决这些问题。鉴于存在大量问题，编者对所提供数据的整体准确性失去了信心。通讯作者 S. Bettuzzi 不同意撤稿决定。其余合著者无法确认撤稿。

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来源期刊

Journal of Cellular Physiology 生物-生理学

CiteScore

14.70

自引率

0.00%

发文量

256

审稿时长

1 months

期刊介绍： The Journal of Cellular Physiology publishes reports of high biological significance in areas of eukaryotic cell biology and physiology, focusing on those articles that adopt a molecular mechanistic approach to investigate cell structure and function. There is appreciation for the application of cellular, biochemical, molecular and in vivo genetic approaches, as well as the power of genomics, proteomics, bioinformatics and systems biology. In particular, the Journal encourages submission of high-interest papers investigating the genetic and epigenetic regulation of proliferation and phenotype as well as cell fate and lineage commitment by growth factors, cytokines and their cognate receptors and signal transduction pathways that influence the expression, integration and activities of these physiological mediators. Similarly, the Journal encourages submission of manuscripts exploring the regulation of growth and differentiation by cell adhesion molecules in addition to the interplay between these processes and those induced by growth factors and cytokines. Studies on the genes and processes that regulate cell cycle progression and phase transition in eukaryotic cells, and the mechanisms that determine whether cells enter quiescence, proliferate or undergo apoptosis are also welcomed. Submission of papers that address contributions of the extracellular matrix to cellular phenotypes and physiological control as well as regulatory mechanisms governing fertilization, embryogenesis, gametogenesis, cell fate, lineage commitment, differentiation, development and dynamic parameters of cell motility are encouraged. Finally, the investigation of stem cells and changes that differentiate cancer cells from normal cells including studies on the properties and functions of oncogenes and tumor suppressor genes will remain as one of the major interests of the Journal.