Association of dietary and lifestyle inflammatory indices with type 2 diabetes risk in Iranian adults.

IF 2.8 3区医学 Q3 ENDOCRINOLOGY & METABOLISM

BMC Endocrine Disorders Pub Date : 2024-08-01 DOI:10.1186/s12902-024-01673-7

Mahdieh Hosseinzadeh, Niloufar Saber, Sakineh Shab Bidar, Sogol Hashemi, Farshad Teymoori, Masoud Mirzaei, Azadeh Nadjarzadeh, Seyedeh Tayebeh Rahideh

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引用次数: 0

Abstract

Background: Type 2 diabetes mellitus (T2DM) is often linked to chronic inflammation, which can be influenced by both lifestyle and dietary choices. However, the relationship between the inflammatory potential of diet and lifestyle factors and the risk of developing T2DM remains unclear. The present study aimed to investigate the associations of the empirical dietary inflammatory index (EDII), dietary inflammatory score (DIS), and lifestyle inflammatory score (LIS) with the risk of T2DM among Iranian adults.

Methods: The current study was conducted on 5714 individuals from Yazd Health Study (YaHS) who were followed up for a mean period of six years. YaHS is a prospective cohort study which has been conducted since 2014. Dietary intakes were collected at baseline using the food frequency questionnaire. The relative risk (RR) of T2DM was calculated by Cox regression analysis across tertiles of EDII, DIS, and LIS, adjusted for potential confounders.

Results: The mean ± SD for the age and body mass index of the study population were 47.0 ± 9.2 years and 26.7 ± 5.1 Kg.m², respectively. A significant association between LIS and the risk of T2DM was observed (RR: 4.05, 95% CI: 2.61-6.27 P-trend < 0.001). Individuals in the highest compared to the lowest tertile of EDII-LIS (RR: 3.07, 95%CI: 2.01-4.68; P for trend < 0.001) and DIS-LIS (RR: 2.42, 95%CI: 1.69-3.49; P for trend < 0.001) had a higher risk of T2DM. However, no significant association was found between EDII and DIS scores and the risk of T2DM.

Conclusion: Greater adherence to LIS, EDII-LIS, and DIS-LIS scores was associated with a higher risk of T2DM, while no significant association was found between EDII and DIS with T2DM risk.

查看原文本刊更多论文

伊朗成年人的饮食和生活方式炎症指数与 2 型糖尿病风险的关系。

背景：2 型糖尿病（T2DM）通常与慢性炎症有关，而慢性炎症可受生活方式和饮食选择的影响。然而，饮食和生活方式因素的炎症潜力与 T2DM 发病风险之间的关系仍不清楚。本研究旨在调查伊朗成年人的经验饮食炎症指数（EDII）、饮食炎症评分（DIS）和生活方式炎症评分（LIS）与 T2DM 风险之间的关系：本研究对来自亚兹德健康研究（YaHS）的 5714 人进行了平均为期六年的跟踪调查。亚兹德健康研究是一项前瞻性队列研究，自 2014 年开始实施。研究人员通过食物频率问卷调查收集了基线饮食摄入量。在对潜在的混杂因素进行调整后，通过Cox回归分析计算了不同EDII、DIS和LIS分层的T2DM相对风险（RR）：研究对象的年龄和体重指数的平均值（± SD）分别为 47.0 ± 9.2 岁和 26.7 ± 5.1 Kg.m2。观察发现，LIS 与 T2DM 风险之间存在明显关联（RR：4.05，95% CI：2.61-6.27 P-trend）：更严格遵守 LIS、EDII-LIS 和 DIS-LIS 评分与更高的 T2DM 风险相关，而 EDII 和 DIS 与 T2DM 风险之间没有发现明显的关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Endocrine Disorders ENDOCRINOLOGY & METABOLISM-

CiteScore

4.40

自引率

0.00%

发文量

280

审稿时长

>12 weeks

期刊介绍： BMC Endocrine Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of endocrine disorders, as well as related molecular genetics, pathophysiology, and epidemiology.

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