Optic nerve head alterations after COVID-19: an optical coherence tomography angiography-based longitudinal study.

IF 1.4 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Journal of International Medical Research Pub Date : 2024-07-01 DOI:10.1177/03000605241263236

Mojtaba Abrishami, Kiana Hassanpour, Kia Bayat, Seyedeh Maryam Hosseini, Nasibeh Amini, Majid Abrishami, Parham Sayyah Ensan, Hamid Reza Heidarzadeh

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引用次数: 0

Abstract

Objective: To evaluate longitudinal changes in peripapillary vessel density (VD) following coronavirus disease 2019 (COVID-19) using optical coherence tomography angiography.

Methods: As part of a prospective longitudinal observational study, we studied healthy individuals with a history of mild COVID-19 confirmed via real-time polymerase chain reaction. After recovery, we used the Optovue RTVue XR Avanti machine to perform optic nerve head (ONH) imaging. We also assessed the VD of all vessels and of small vessels in the disc and the radial peripapillary capillary (RPC) network at 1 and 3 months post-recovery.

Results: We included 17 patients (34 eyes; mean age: 36.9 ± 10.2 years, range: 24-62 years) who had recovered from COVID-19. No changes were observed in the ONH parameters. However, there was a noticeable trend of increased small vessel VD values in the RPC. These increases were significant for the peripapillary whole, superior hemifield, inferior-temporal, temporal-superior, and superior-temporal small vessels. Moreover, the evaluation of all vessel VD values in the RPC revealed a significant decrease in the inside disc and a significant increase in a grid-based inferior region.

Conclusion: COVID-19 may affect VD of the RPC in the ONH, and should be considered in ONH evaluations.

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COVID-19 后视神经头的改变：基于光学相干断层血管造影术的纵向研究。

目的：利用光学相干断层血管造影术评估 2019 年冠状病毒病（COVID-19）后毛细血管周围密度（VD）的纵向变化：使用光学相干断层血管造影术评估2019年冠状病毒病（COVID-19）后毛细血管周围密度（VD）的纵向变化：作为前瞻性纵向观察研究的一部分，我们研究了经实时聚合酶链式反应证实有轻度COVID-19病史的健康人。康复后，我们使用 Optovue RTVue XR Avanti 机器进行视神经头（ONH）成像。我们还在康复后 1 个月和 3 个月评估了所有血管、视盘小血管和径向毛细血管网（RPC）的 VD：我们共纳入了 17 名从 COVID-19 中康复的患者（34 眼；平均年龄：36.9 ± 10.2 岁，范围：24-62 岁）。视网膜上皮参数没有发生变化。但是，RPC 中的小血管 VD 值有明显增加的趋势。这些增加在整个毛细血管周围、上半视野、下颞、颞上和上颞小血管中都很明显。此外，对 RPC 中的所有血管 VD 值进行评估后发现，内盘的血管 VD 值显著下降，而网格状的下部区域的血管 VD 值显著上升：结论：COVID-19 可能会影响视网膜病变中 RPC 的 VD 值，在视网膜病变评估中应加以考虑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of International Medical Research 医学-药学

CiteScore

3.20

自引率

0.00%

发文量

555

审稿时长

1 months

期刊介绍： _Journal of International Medical Research_ is a leading international journal for rapid publication of original medical, pre-clinical and clinical research, reviews, preliminary and pilot studies on a page charge basis. As a service to authors, every article accepted by peer review will be given a full technical edit to make papers as accessible and readable to the international medical community as rapidly as possible. Once the technical edit queries have been answered to the satisfaction of the journal, the paper will be published and made available freely to everyone under a creative commons licence. Symposium proceedings, summaries of presentations or collections of medical, pre-clinical or clinical data on a specific topic are welcome for publication as supplements. Print ISSN: 0300-0605