Malaria Control Programme in Nigeria: uptake of prevention strategies - a systematic review

Collins Ugwu, N. Ugwu, Ogbonnaya Ogbu, O. Chukwu, N. Chika-Igwenyi, Olaronke Afolabi, Daniel Igwe, Esther Ekwe, Ngozi Ezekwesili, C. Uneke, G. Isiguzo
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Abstract

Background: Malaria presents a colossal burden to Africa, including Nigeria. The objective of this study was to review relevant publications to identify specific malaria control strategies in Nigeria and to determine their level of uptake. Methods: A Medline Entrez Pubmed search was conducted to identify studies from July 2013 to June 2018 investigating malaria control strategies. The search yielded 123 publications and twelve publications that met the inclusion criteria were systematically reviewed and results presented. Results: Five publications investigated the level of uptake of IPTp-SP and all reported low uptake of IPTp-SP. Five other publications investigated the uptake of LLINs, of which two reported good uptake. Two studies were on the uptake of mRDT or microscopy before Artemesinin-based combination therapy (ACT) and reported good uptake. Factors associated with poor uptake of malaria preventive strategies included a poorly-financed and poorly structured healthcare system, poor antenatal clinic visits, unavailability of the antimalaria drugs and nets, ignorance, poverty, cultural/religious belief and cost of mRDT and microscopy. Conclusion: Though malaria control strategies are available in Nigeria, there was insufficient uptake of these preventive strategies. Awareness creation and education on the importance of preventive strategies and their efficient utilization will help reduce Nigeria’s malaria burden. Keywords: Anaemia; malaria control strategies; Nigeria; Uptake.
尼日利亚疟疾控制计划:预防战略的采用情况--系统审查
背景:疟疾给包括尼日利亚在内的非洲带来了巨大的负担。本研究的目的是审查相关出版物,以确定尼日利亚的具体疟疾控制策略,并确定其采用水平。研究方法对 Medline Entrez Pubmed 进行了检索,以确定 2013 年 7 月至 2018 年 6 月期间调查疟疾控制策略的研究。搜索结果显示有 123 篇出版物,对符合纳入标准的 12 篇出版物进行了系统性审查,并提交了审查结果。结果:五篇出版物调查了IPTp-SP的吸收水平,所有出版物均报告了IPTp-SP的低吸收率。另有五份出版物调查了长效驱虫蚊帐的使用情况,其中两份报告了良好的使用情况。有两项研究是关于青蒿素类复方疗法(ACT)前使用 mRDT 或显微镜检查的情况,并报告了良好的使用情况。与疟疾预防策略使用率低有关的因素包括:医疗保健系统资金短缺、结构不完善、产前门诊量低、抗疟疾药物和蚊帐供应不足、无知、贫困、文化/宗教信仰以及移动射线荧光检测和显微镜检查的费用。结论:虽然尼日利亚有疟疾控制策略,但这些预防策略的使用率并不高。就预防策略的重要性及其有效利用进行宣传和教育,将有助于减轻尼日利亚的疟疾负担。关键词贫血;疟疾控制策略;尼日利亚;吸收。
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