The case of development of HIV-associated Kaposi's sarcoma with skin and lung lesions

M. Kobernik, V. Nikolenko, O. E. Mikova, A. A. Zavyalova, M. A. Pyankova
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Abstract

A clinical case of HIV-associated Kaposi's sarcoma with skin and lung lesions is presented. A patient referred to the Perm Regional Center for the Prevention and Control of AIDS and Infectious Diseases complaining of rash on the skin of the right wing of the nose, forehead, in the right axillary and right inguinal areas, on the shins. The first skin changes occurred in December 2020 on the right wing of the nose, later the pathological process spread to other areas of the skin. HIV was revealed in 2009 and the patient had not received specialized medical care until 2022 as he had been in prison. Since March 2022, the patient has been registered at the dispensary and regularly receives antiretroviral therapy. In April 2022, PET/CT tests and histological examination of a biopsy of skin rashes were performed. On the basis of these findings the diagnosis of Kaposi's sarcoma with skin and lungs lesions was made. HIV-associated Kaposi's sarcoma is accompanied by lesions of the skin and internal organs. Skin changes in Kaposi's sarcoma are characterized by the primary localization of foci on the face and upper extremities, and without antiretroviral therapy, by rapid progression and generalization of the pathological process. Visceral lesions worsen the course of the disease and complicate its prognosis. Patients with HIV-associated Kaposi's sarcoma need dynamic monitoring and complex therapy from infectious diseases specialists, dermatovenerologists, oncologists.
伴有皮肤和肺部病变的艾滋病毒相关卡波西肉瘤病例
本文介绍了一例伴有皮肤和肺部病变的艾滋病病毒相关卡波西肉瘤临床病例。患者转诊至彼尔姆地区艾滋病和传染病预防控制中心,主诉鼻翼右侧、前额、右腋窝和右腹股沟区、小腿皮肤出现皮疹。2020 年 12 月,患者鼻翼右侧皮肤首次出现变化,随后病理过程扩散到其他皮肤部位。患者于 2009 年发现感染艾滋病毒,由于一直在监狱服刑,直到 2022 年才接受专门的医疗护理。自 2022 年 3 月起,患者在医务室登记并定期接受抗逆转录病毒治疗。2022 年 4 月,对皮疹进行了 PET/CT 检测和活组织检查。根据这些检查结果,诊断为伴有皮肤和肺部病变的卡波西肉瘤。与艾滋病毒相关的卡波西肉瘤伴有皮肤和内脏器官的病变。卡波西肉瘤皮肤病变的特点是病灶主要发生在面部和上肢,在没有抗逆转录病毒治疗的情况下,病变会迅速发展和泛化。内脏病变会加重病程并使预后复杂化。艾滋病毒相关卡波西肉瘤患者需要传染病专家、皮肤科医生和肿瘤科医生的动态监测和综合治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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