Prevalence of respiratory distress syndrome in premature twins compared to premature singletons

Q2 Medicine

Medicinski Glasnik Pub Date : 2024-07-23 DOI:10.17392/1638-21-02

Emina Hadžimuratović, Amina Selimović, Admir Hadžimuratović, V. Mišanović, Velma Rebić, Lejla Kurtalić

{"title":"Prevalence of respiratory distress syndrome in premature twins compared to premature singletons","authors":"Emina Hadžimuratović, Amina Selimović, Admir Hadžimuratović, V. Mišanović, Velma Rebić, Lejla Kurtalić","doi":"10.17392/1638-21-02","DOIUrl":null,"url":null,"abstract":"\n Aim To estimate prevalence of respiratory distress syndrome in preterm twins compared to preterm singletons.  Methods This is a retrospective observational point prevalence study conducted at the level of three neonatal intensive care units. Medical records of all preterm newborns (<37 weeks of gestation) with respiratory distress syndrome treated in a two-year period were reviewed. The birth order of twins, gestational age and mortality were analyzed. Results Out of 809 preterm newborns, 104 (12.9%) were twins. Median gestational age at birth was 30.3 (IQR 31.4–34.2) weeks. Respiratory distress syndrome was diagnosed in 525 (64.9 %) preterm newborns, of which 441 singletons and 84 twins. Prevalence of respiratory distress syndrome in first-born twins was not significantly higher compared with singletons, 67.3% (35/52) vs. 62.6 % (441/705), respectively (p=0.06). Prevalence of respiratory distress syndrome in second-born twins was 94.2 % (49/52), which was significantly higher compared with both singletons and first-born twins (p<0.001). The mortality rate of preterm newborns was significantly higher in second-born twins compared with singletons and first-born twins, 15.4 % vs. 6.8 %  (p<0.001) and 15.4 % vs. 5.5% (p<0.001), respectively.  Conclusion There was a higher risk of respiratory distress syndrome and higher mortality rate in twins compared with singletons, but only in second-born twins the difference was statistically significant.\n","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"57 11","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicinski Glasnik","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17392/1638-21-02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Aim To estimate prevalence of respiratory distress syndrome in preterm twins compared to preterm singletons.
Methods This is a retrospective observational point prevalence study conducted at the level of three neonatal intensive care units. Medical records of all preterm newborns (<37 weeks of gestation) with respiratory distress syndrome treated in a two-year period were reviewed. The birth order of twins, gestational age and mortality were analyzed.
Results Out of 809 preterm newborns, 104 (12.9%) were twins. Median gestational age at birth was 30.3 (IQR 31.4–34.2) weeks. Respiratory distress syndrome was diagnosed in 525 (64.9 %) preterm newborns, of which 441 singletons and 84 twins. Prevalence of respiratory distress syndrome in first-born twins was not significantly higher compared with singletons, 67.3% (35/52) vs. 62.6 % (441/705), respectively (p=0.06). Prevalence of respiratory distress syndrome in second-born twins was 94.2 % (49/52), which was significantly higher compared with both singletons and first-born twins (p<0.001). The mortality rate of preterm newborns was significantly higher in second-born twins compared with singletons and first-born twins, 15.4 % vs. 6.8 % (p<0.001) and 15.4 % vs. 5.5% (p<0.001), respectively.
Conclusion There was a higher risk of respiratory distress syndrome and higher mortality rate in twins compared with singletons, but only in second-born twins the difference was statistically significant.

查看原文本刊更多论文

早产双胞胎与早产单胎的呼吸窘迫综合征患病率比较

目的与早产儿单胎相比，估计早产儿双胎呼吸窘迫综合征的患病率方法这是一项回顾性观察点患病率研究，在三个新生儿重症监护室进行。研究回顾了两年内治疗的所有患有呼吸窘迫综合征的早产新生儿（孕 37 周）的病历。结果在 809 名早产新生儿中，有 104 名（12.9%）是双胞胎。中位胎龄为 30.3 周（IQR 31.4–34.2）。525名（64.9%）早产新生儿被诊断出呼吸窘迫综合征，其中441名是单胎，84名是双胞胎。与单胎相比，头胎双胞胎的呼吸窘迫综合征发病率并无明显增加，分别为 67.3%（35/52）对 62.6%（441/705）（P=0.06）。二胎双胞胎的呼吸窘迫综合征发病率为 94.2%（49/52），与单胎和头胎双胞胎相比明显更高（p<0.001）。与单胎和头胎双胞胎相比，二胎双胞胎早产新生儿的死亡率明显更高，分别为 15.4% vs. 6.8% （p<0.001）和 15.4% vs. 5.5% （p<0.001）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Medicinski Glasnik 医学-医学：内科

CiteScore

2.30

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Medicinski Glasnik (MG) is the official publication (two times per year) of the Medical Association of Zenica-Doboj Canton. Manuscripts that present of original basic and applied research from all fields of medicine (general and clinical practice, and basic medical sciences) are invited.