Non-Invasive Analysis of the Bioelectrical Impedance of a Human Forearm

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
D. Plonis, Edas Kalinauskas, A. Katkevičius, A. Krukonis
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Abstract

This study explores the practical application and impact of bioimpedance analysis in mobile devices for monitoring human health. The objective of the study is to propose a feasible application of non-invasive bioimpedance analysis by using the tetrapolar electrode connection method and the Cole–Cole model. Bioimpedance measurements and the calculation of electrical parameters are performed using ANSYS HFSS software for theoretical calculations and digital signal processing technology for real-time measurements using hardware devices. The study focuses on a model of the front arm, including tissues such as bone, fat, muscles, arteries and skin, with glucose concentrations as test cases. The simulated characteristic impedance with the ANSYS HFSS software package at 125 kHz varied from 315.8 Ω to 312.6 Ω, and the measured forearm characteristic impedance with hardware varied from 150.1 Ω to 151.3 Ω. The measured characteristic impedance when the heart is in systole and diastole also differed, with a difference of about 0.85% of the maximum impedance measured. The study demonstrates the potential of non-invasive bioimpedance analysis to address health issues such as obesity and heart disease. It also highlights its usefulness as a non-invasive alternative for measuring glucose concentration in diabetic patients to reduce the risk of infection. The findings indicate the feasibility of using bioimpedance analysis in mobile devices for health monitoring purposes.
人体前臂生物电阻抗的非侵入式分析
本研究探讨了生物阻抗分析在监测人体健康的移动设备中的实际应用及其影响。研究的目的是通过使用四极电极连接方法和科尔-科尔模型,提出无创生物阻抗分析的可行应用。生物阻抗测量和电气参数计算使用 ANSYS HFSS 软件进行理论计算,并使用数字信号处理技术利用硬件设备进行实时测量。研究重点是前臂模型,包括骨、脂肪、肌肉、动脉和皮肤等组织,并以葡萄糖浓度作为测试案例。使用 ANSYS HFSS 软件包在 125 kHz 频率下模拟的特征阻抗从 315.8 Ω 到 312.6 Ω 不等,而使用硬件测量的前臂特征阻抗从 150.1 Ω 到 151.3 Ω 不等。当心脏处于收缩期和舒张期时测量的特征阻抗也有所不同,最大阻抗测量值相差约 0.85%。这项研究证明了无创生物阻抗分析在解决肥胖和心脏病等健康问题方面的潜力。它还强调了生物阻抗分析作为测量糖尿病患者血糖浓度的无创替代方法的实用性,以降低感染风险。研究结果表明,在移动设备中使用生物阻抗分析进行健康监测是可行的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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