Profile Hemodynamic and Use Vasoactive Drugs in Critical Sepsis Patients in the Inpatient Unit of RSUD Dr. Soetomo Period 1 February - 31 March 2023

Abstract

Background: Patients in critical condition often require intensive care, including ventilatory support, organ/system function assistance, and the administration of vasoactive drugs. Sepsis, a severe and potentially fatal condition marked by organ dysfunction, occurs when the body's response to infection becomes uncontrolled. Vasoactive drugs, which include vasopressors and inotropes, are commonly used in these patients to improve hemodynamic stability and ensure adequate blood flow to organs. Objective: To understand the profile hemodynamic and use vasoactive drugs in critical sepsis patients in the inpatient unit of RSUD Dr. Soetomo period 1 February – 31 March 2023. Method: The research was conducted prospectively on sepsis patients who used vasoactive drugs in the period 1 February 2023 – 31 March 2023 at RSUD Dr. Soetomo, Surabaya. All data is collected from medical records, sampling is carried out using the Accidental Sampling technique by taking demographic data and clinical data of patients, the use of vasoactive drugs in critical septic patients and recording the results of medical records that will be recorded. Results: Overall, 65 patients were included in this study (52.31% female and 47.69% male). The most commonly used vasoactive drug was norepinephrine at 64.62%, and the combination of norepinephrine and vasopressin was used in 16.90% of cases. Conclusions: The findings suggest that the use of vasoactive drugs is a crucial component in the resuscitation of septic shock patients, involving the administration of vasopressor medications and intravenous fluids. This approach aims to achieve the desired hemodynamic stability in septic shock patients experiencing severe hypotension. Norepinephrine was the most commonly used vasoactive drug at Dr. Soetomo Regional General Hospital in Surabaya. Keywords: Sepsis, critical patients, hemodynamics, vasoactive drugs