Peristomal skin lesions - identifying patients at risk.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-11-01 Epub Date: 2024-07-29 DOI:10.1055/a-2360-5099
Louisa Dietmaier, Scarlett Summa, Moritz Ronicke, Cornelia Erfurt-Berge
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Abstract

Background and objectives: Diagnosis and therapy of peristomal skin lesions are challenging for the majority of therapists. Established diagnostic tools have not yet been validated. Our objective was to outline the spectrum of and to identify risk factors for skin lesions in ostomy patients. A focus was set on peristomal ulcerations and their differentiation as peristomal pyoderma gangrenosum.

Methods: In a retrospective analysis, frequency and character of peristomal skin lesions in patients presenting at two departments were analysed. Patients suffering from peristomal ulcerations were subjected to a more detailed analysis including application of the PARACELSUS score.

Results: A total of 565 patients with ostomy were analysed; 40.2% (n = 227) presented with peristomal skin lesions. Moisture-associated skin damage (27.9%) was the most common, while ulcerations (21.9%) and eczematous skin alterations (19.1%) were seen with comparable frequency. Peristomal pyoderma gangrenosum was diagnosed in 7.9% of all observed peristomal lesions. Among patients with inflammatory bowel disease (n = 98), peristomal ulcerations were the leading finding (35.7%), and pyoderma gangrenosum was more frequent in these patients (16.3%).

Conclusions: It is necessary to assess and classify peristomal skin lesions. Further studies for the validation of different scores or the development of diagnostic tools are needed.

肛周皮损--识别高危患者。
背景和目的:对于大多数治疗师来说,肛周皮肤病变的诊断和治疗都具有挑战性。既定的诊断工具尚未得到验证。我们的目标是概述造口患者皮肤损伤的范围并确定风险因素。重点是造口周围溃疡及其与造口周围脓皮病的鉴别:在一项回顾性分析中,分析了在两个科室就诊的造口周围皮肤损伤的频率和特征。对肛周溃疡患者进行了更详细的分析,包括应用 PARACELSUS 评分:共对 565 名造口患者进行了分析,其中 40.2%(n = 227)的患者出现造口周围皮肤损伤。水分相关性皮肤损伤(27.9%)最为常见,而溃疡(21.9%)和湿疹性皮肤改变(19.1%)的出现频率相当。在所有观察到的肛周病变中,7.9%被诊断为肛周脓皮病。在炎症性肠病患者(98 人)中,肛周溃疡是最主要的发现(35.7%),脓皮病在这些患者中更为常见(16.3%):结论:有必要对肛周皮肤病变进行评估和分类。结论:有必要对肛周皮肤病变进行评估和分类,需要进一步研究验证不同的评分或开发诊断工具。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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