Alcohol hangover versus dehydration revisited: The effect of drinking water to prevent or alleviate the alcohol hangover

IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY
Marlou Mackus , Ann-Kathrin Stock , Johan Garssen , Andrew Scholey , Joris C. Verster
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Abstract

The alcohol hangover is a combination of negative mental and physical symptoms which can be experienced after a single episode of alcohol consumption, starting when blood alcohol concentration (BAC) approaches zero. A popular theory suggests that dehydration is the primary cause of alcohol hangover and that the consumption of water could alleviate hangover symptoms. Here, the current evidence on the relationship between hangover severity, thirst, and water consumption is summarized. The positive correlations of the amount of water consumed with both hangover severity and thirst suggest that both dehydration and the hangover are co-occurring after-effects of alcohol consumption. While hangovers were typically relatively enduring, dehydration effects were usually mild and short-lasting. Survey data revealed that water consumption during or directly after alcohol consumption had only a modest effect in preventing next-day hangover. Also, the amount of water consumed during hangover was not related to changes of hangover severity and thirst. Thus, water consumption was not effective to alleviate the alcohol hangover. Taken together, these data suggests that alcohol hangover and dehydration are two co-occurring but independent consequences of alcohol consumption.

重新审视宿醉与脱水:喝水对预防或缓解宿醉的影响。
酒精宿醉是指一次饮酒后,当血液中酒精浓度(BAC)接近零时开始出现的一系列心理和生理上的不良症状。一种流行的理论认为,脱水是酒精宿醉的主要原因,而喝水可以缓解宿醉症状。在此,我们总结了宿醉严重程度、口渴和饮水量之间关系的现有证据。饮水量与宿醉严重程度和口渴程度呈正相关,这表明脱水和宿醉是饮酒后同时出现的后遗症。宿醉通常比较持久,而脱水效应通常比较轻微且持续时间较短。调查数据显示,在饮酒期间或饮酒后直接喝水对预防第二天宿醉的影响不大。此外,宿醉期间的饮水量与宿醉严重程度和口渴程度的变化无关。因此,喝水并不能有效缓解酒精宿醉。综上所述,这些数据表明,宿醉和脱水是饮酒后同时出现但又相互独立的两种后果。
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来源期刊
Alcohol
Alcohol 医学-毒理学
CiteScore
4.60
自引率
4.30%
发文量
74
审稿时长
15.6 weeks
期刊介绍: Alcohol is an international, peer-reviewed journal that is devoted to publishing multi-disciplinary biomedical research on all aspects of the actions or effects of alcohol on the nervous system or on other organ systems. Emphasis is given to studies into the causes and consequences of alcohol abuse and alcoholism, and biomedical aspects of diagnosis, etiology, treatment or prevention of alcohol-related health effects. Intended for both research scientists and practicing clinicians, the journal publishes original research on the neurobiological, neurobehavioral, and pathophysiological processes associated with alcohol drinking, alcohol abuse, alcohol-seeking behavior, tolerance, dependence, withdrawal, protracted abstinence, and relapse. In addition, the journal reports studies on the effects alcohol on brain mechanisms of neuroplasticity over the life span, biological factors associated with adolescent alcohol abuse, pharmacotherapeutic strategies in the treatment of alcoholism, biological and biochemical markers of alcohol abuse and alcoholism, pathological effects of uncontrolled drinking, biomedical and molecular factors in the effects on liver, immune system, and other organ systems, and biomedical aspects of fetal alcohol spectrum disorder including mechanisms of damage, diagnosis and early detection, treatment, and prevention. Articles are published from all levels of biomedical inquiry, including the following: molecular and cellular studies of alcohol''s actions in vitro and in vivo; animal model studies of genetic, pharmacological, behavioral, developmental or pathophysiological aspects of alcohol; human studies of genetic, behavioral, cognitive, neuroimaging, or pathological aspects of alcohol drinking; clinical studies of diagnosis (including dual diagnosis), treatment, prevention, and epidemiology. The journal will publish 9 issues per year; the accepted abbreviation for Alcohol for bibliographic citation is Alcohol.
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