Translational control of papillomavirus mRNAs in the spotlight.

IF 13 1区生物学 Q1 CELL BIOLOGY

Trends in Cell Biology Pub Date : 2024-09-01 Epub Date: 2024-07-27 DOI:10.1016/j.tcb.2024.07.001

Alejandra García, Giovanna Maldonado, Greco Hernández

引用次数: 0

Abstract

High-risk human papillomaviruses (HPVs) cause most cases of cervical cancer, a disease with an increasing impact worldwide. Recent studies have shown that the synthesis of viral oncoproteins is strongly subject to translational control. Thus, targeting the protein synthesis machinery might open novel avenues to develop innovative therapies aiming to improve patients' survival.

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聚光灯下的乳头瘤病毒 mRNA 翻译控制。

高危人乳头瘤病毒（HPV）是导致大多数宫颈癌病例的原因，这种疾病对全世界的影响越来越大。最近的研究表明，病毒癌蛋白的合成在很大程度上受制于翻译控制。因此，以蛋白质合成机制为靶点可能会为开发创新疗法开辟新的途径，从而提高患者的生存率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Cell Biology 生物-细胞生物学

CiteScore

32.00

自引率

0.50%

发文量

160

审稿时长

61 days

期刊介绍： Trends in Cell Biology stands as a prominent review journal in molecular and cell biology. Monthly review articles track the current breadth and depth of research in cell biology, reporting on emerging developments and integrating various methods, disciplines, and principles. Beyond Reviews, the journal features Opinion articles that follow trends, offer innovative ideas, and provide insights into the implications of new developments, suggesting future directions. All articles are commissioned from leading scientists and undergo rigorous peer-review to ensure balance and accuracy.