{"title":"Efficient Cu‐Based Mixed Oxides Catalyst for α‐Alkylation of Ketones with Alcohols","authors":"Lina Zhang , Denghong Yao , Xue Wang , Dong Zhang","doi":"10.1002/ajoc.202400350","DOIUrl":null,"url":null,"abstract":"<div><div>A series of Cu‐based mixed oxides were prepared by calcinations of corresponding CuMgAl‐layered double hydroxides precursors at different temperatures with nominal Cu/Mg/Al ratios of 1 : 1 : 2(Cu‐LDH‐1), 1 : 2 : 1(Cu‐LDH‐2),1 : 1 : 1(Cu‐LDH‐3), and 2 : 1 : 1(Cu‐LDH‐4). The synthesized catalysts were characterized using X‐ray diffraction, high‐resolution transmission electron microscopy, scanning electron microscopy, X‐ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, inductively coupled plasma atomic emission spectroscopy (ICP‐AES), and N<sub>2</sub> physisorption analysis techniques. All as‐obtained catalysts showed adequate catalytic performance for the α‐alkylation of ketones with alcohols through a hydrogen autotransfer mechanism. The catalyst CuMgAl‐I‐650 (obtained by calcining Cu‐LDH‐1 at 650 °C) displayed the highest activity and selectivity. Using this catalyst system, a wide range of branched ketones were synthesized in good to excellent isolated yields. Moreover, the catalyst CuMgAl‐I‐650 could be recycled and reutilized for four cycles without any significant loss of activity and selectivity. This study provides a very simple and inexpensive catalysis based on transition metals, which are in abundance on earth.</div></div>","PeriodicalId":130,"journal":{"name":"Asian Journal of Organic Chemistry","volume":"13 11","pages":"Article e202400350"},"PeriodicalIF":2.8000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S2193580724004008","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
A series of Cu‐based mixed oxides were prepared by calcinations of corresponding CuMgAl‐layered double hydroxides precursors at different temperatures with nominal Cu/Mg/Al ratios of 1 : 1 : 2(Cu‐LDH‐1), 1 : 2 : 1(Cu‐LDH‐2),1 : 1 : 1(Cu‐LDH‐3), and 2 : 1 : 1(Cu‐LDH‐4). The synthesized catalysts were characterized using X‐ray diffraction, high‐resolution transmission electron microscopy, scanning electron microscopy, X‐ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, inductively coupled plasma atomic emission spectroscopy (ICP‐AES), and N2 physisorption analysis techniques. All as‐obtained catalysts showed adequate catalytic performance for the α‐alkylation of ketones with alcohols through a hydrogen autotransfer mechanism. The catalyst CuMgAl‐I‐650 (obtained by calcining Cu‐LDH‐1 at 650 °C) displayed the highest activity and selectivity. Using this catalyst system, a wide range of branched ketones were synthesized in good to excellent isolated yields. Moreover, the catalyst CuMgAl‐I‐650 could be recycled and reutilized for four cycles without any significant loss of activity and selectivity. This study provides a very simple and inexpensive catalysis based on transition metals, which are in abundance on earth.
期刊介绍:
Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC)
The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.