A new calibration method of an array of plastic scintillating fibers for dosimetry in electron FLASH Radiotherapy

IF 1.6 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY
E. Ravera , A. Cavalieri , E. Ciarrocchi , D. Del Sarto , F. Di Martino , M. Massa , L. Masturzo , A. Moggi , M. Morrocchi , J.H. Pensavalle , M.G. Bisogni
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引用次数: 0

Abstract

The challenge of saturation at the high dose rate employed in FLASH radiotherapy and the lack of real-time 2D and 3D dosimeters create an opportunity for the use of plastic scintillators. This study presents the development of an online dosimetric system designed for electron FLASH radiotherapy applications: an array of dosimeters, made by plastic scintillating fibers, each one coupled to an optical fiber, was evaluated as a proof-of-concept using a LINAC providing 9 MeV electrons, at the Centro Pisano Flash Radiotherapy. Signal linearity was established up to 10 Gy/pulse, with a pulse duration of 4μs. We also measured the signal variation across the beam profile using different applicators (30 mm, 50 mm and 100 mm in diameters) and we developed a geometrical model that accounts for the different amount of dose absorbed by the plastic scintillating fibers and the optical fibers. By fitting this model to the data, we estimated both the inter-calibration factors of the dosimeters, as well as the intrinsic ratio (i.e. for equal irradiated volumes) of spurious light in the optical fiber respect to the scintillation, which is equal to (4.7±0.1stat.±1.0syst.) %.

用于电子闪烁放射疗法剂量测定的塑料闪烁纤维阵列校准新方法
FLASH 放射治疗中使用的高剂量率饱和问题以及实时二维和三维剂量计的缺乏为塑料闪烁体的使用创造了机会。本研究介绍了专为电子闪烁放射治疗应用而设计的在线剂量测定系统的开发情况:在皮萨诺闪烁放射治疗中心(Centro Pisano Flash Radiotherapy),使用提供 9 MeV 电子的 LINAC 对塑料闪烁纤维制成的剂量计阵列进行了概念验证评估。我们还测量了使用不同涂抹器(直径分别为 30 毫米、50 毫米和 100 毫米)时整个光束剖面上的信号变化,并建立了一个几何模型,用于解释塑料闪烁纤维和光纤吸收的不同剂量。通过将该模型与数据拟合,我们估算出了剂量计的校准系数,以及光纤中杂散光与闪烁光的固有比率(即在等量照射的情况下),该比率等于 (4.7)%。
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来源期刊
Radiation Measurements
Radiation Measurements 工程技术-核科学技术
CiteScore
4.10
自引率
20.00%
发文量
116
审稿时长
48 days
期刊介绍: The journal seeks to publish papers that present advances in the following areas: spontaneous and stimulated luminescence (including scintillating materials, thermoluminescence, and optically stimulated luminescence); electron spin resonance of natural and synthetic materials; the physics, design and performance of radiation measurements (including computational modelling such as electronic transport simulations); the novel basic aspects of radiation measurement in medical physics. Studies of energy-transfer phenomena, track physics and microdosimetry are also of interest to the journal. Applications relevant to the journal, particularly where they present novel detection techniques, novel analytical approaches or novel materials, include: personal dosimetry (including dosimetric quantities, active/electronic and passive monitoring techniques for photon, neutron and charged-particle exposures); environmental dosimetry (including methodological advances and predictive models related to radon, but generally excluding local survey results of radon where the main aim is to establish the radiation risk to populations); cosmic and high-energy radiation measurements (including dosimetry, space radiation effects, and single event upsets); dosimetry-based archaeological and Quaternary dating; dosimetry-based approaches to thermochronometry; accident and retrospective dosimetry (including activation detectors), and dosimetry and measurements related to medical applications.
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