Staged Regenerative-Phenotype Modification Therapy for Multiple RT3 Gingival Recessions in Periodontally Compromised Anterior Mandibular Teeth: A Case Report.

Taito Watanabe, Akira Hasuike, Yudai Ogawa, Shayan Barootchi, Shuichi Sato, Lorenzo Tavelli
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Abstract

We report the successful treatment of multiple recession type (RT) 3 gingival recessions in periodontally compromised mandibular anterior teeth with limited keratinized tissue. A 35-yearold man with stage III, grade C periodontitis underwent a two-stage intervention. Initially, a modification of the connective tissue graft (m-CTG) wall technique was used as part of phenotype modification therapy. The CTG acted as a protective 'wall,' securing space for periodontal regeneration, enhancing root coverage, soft tissue thickness, and keratinized mucosal width. Recombinant human fibroblast growth factor-2 and carbonate apatite promoted periodontal regeneration. This procedure successfully facilitated periodontal regeneration, resulting in the transition from RT3 to RT2 gingival recession and adequate keratinized mucosal width. Eighteen months later, the second surgery used a tunneled coronally advanced flap (TCAF) for root coverage. TCAF involved combining a coronally advanced flap and tunnel technique by elevating the trapezoidal surgical papilla and using a de-epithelialized CTG inserted beneath the tunneled flap. Root conditioning with ethylenediaminetetraacetic acid and enamel matrix derivative gel application were performed. Consequently, mean CAL gain was 5.3 mm, mean root coverage was 4.5 mm in height, and the gingival phenotype improved at the treated sites by the 12-month follow-up. This staged approach addresses the challenges of treating RT3 gingival recession with promising outcomes.

针对牙周受损的下颌前牙多发性 RT3 牙龈退缩的分阶段再生表型修正疗法:病例报告。
我们报告了对角化组织有限、牙周受损的下颌前牙多发性牙龈退缩(RT)3 型的成功治疗。一名 35 岁的男子患有 III 期 C 级牙周炎,接受了两阶段干预。首先,作为表型改变疗法的一部分,采用了结缔组织移植(m-CTG)墙技术。结缔组织移植起到保护 "墙 "的作用,确保牙周再生的空间,提高牙根覆盖率、软组织厚度和角化粘膜宽度。重组人成纤维细胞生长因子-2 和碳酸盐磷灰石促进了牙周再生。这次手术成功地促进了牙周再生,使牙龈退缩从 RT3 过渡到 RT2,并获得了足够的角化粘膜宽度。18 个月后,第二次手术使用了隧道式冠状前移皮瓣(TCAF)进行牙根覆盖。隧道式牙冠前移皮瓣将牙冠前移皮瓣和隧道技术相结合,抬高梯形手术乳头,并在隧道式皮瓣下方插入去上皮的 CTG。使用乙二胺四乙酸进行牙根调节,并涂抹釉质基质衍生物凝胶。结果,平均 CAL 增量为 5.3 毫米,平均牙根覆盖高度为 4.5 毫米,治疗部位的牙龈表型在 12 个月的随访中得到了改善。这种分阶段的方法解决了治疗 RT3 牙龈退缩的难题,并取得了良好的效果。
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