The Human Glycome Atlas project for cataloging all glycan-related omics data in human.

IF 3.4 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Glycobiology Pub Date : 2024-09-30 DOI:10.1093/glycob/cwae052

Kiyoko F Aoki-Kinoshita, Yukie Akune-Taylor, Hiromune Ando, Kiyohiko Angata, Morihisa Fujita, Jun-Ichi Furukawa, Hiroyuki Kaji, Koichi Kato, Ken Kitajima, Yasuhiko Kizuka, Yusuke Matsui, Kazuki Nakajima, Shoko Nishihara, Tetsuya Okajima, Kazuma Sakamoto, Chihiro Sato, Morten Thaysen-Andersen, Akira Togayachi, Hirokazu Yagi, Achille Zappa, Kenji Kadomatsu

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引用次数: 0

Abstract

The Human Glycome Atlas (HGA) Project was launched in April 2023, spearheaded by three Japanese institutes: the Tokai National Higher Education and Research System, the National Institutes of Natural Sciences, and Soka University. This was the first time that a field in the life sciences was adopted by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) for a Large-scale Academic Frontiers Promotion Project. This project aims to construct a knowledgebase of human glycans and glycoproteins as a standard for the human glycome. A high-throughput pipeline for comprehensively analyzing 20,000 blood samples in its first five years is planned, at which time an access-controlled version of a human glycomics knowledgebase, called TOHSA, will be released. By the end of the final tenth year, TOHSA will provide a central resource linking human glycan data with other omics data including disease-related information.

查看原文本刊更多论文

人类糖类图谱项目（Human Glycome Atlas Project），用于对人类所有与糖类相关的 Omics 数据进行编目。

2023 年 4 月，由东海国立高等教育研究系统、国立自然科学研究所和创价大学三家日本研究机构牵头，启动了人类糖类图谱（HGA）项目。这是生命科学领域首次被文部科学省（MEXT）采纳为大型学术前沿推进项目。该项目旨在构建人类聚糖和糖蛋白知识库，作为人类糖结果的标准。计划在头五年建立一个高通量管道，对 20,000 份血液样本进行全面分析，届时将发布一个名为 TOHSA 的人类糖学知识库的访问控制版本。到最后十年结束时，TOHSA 将提供一个中央资源，将人类糖类数据与包括疾病相关信息在内的其他 omics 数据联系起来。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Glycobiology 生物-生化与分子生物学

CiteScore

7.50

自引率

4.70%

发文量

审稿时长

3 months

期刊介绍： Established as the leading journal in the field, Glycobiology provides a unique forum dedicated to research into the biological functions of glycans, including glycoproteins, glycolipids, proteoglycans and free oligosaccharides, and on proteins that specifically interact with glycans (including lectins, glycosyltransferases, and glycosidases). Glycobiology is essential reading for researchers in biomedicine, basic science, and the biotechnology industries. By providing a single forum, the journal aims to improve communication between glycobiologists working in different disciplines and to increase the overall visibility of the field.