Effect of quince seed gum (QSG) on the performance of injectable hyaluronic acid hydrogels in terms of the rheological, morphological, and mechanical aspect.

IF 1.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Turkish Journal of Chemistry Pub Date : 2024-05-29 eCollection Date: 2024-01-01 DOI:10.55730/1300-0527.3669

Serdar Kolay, Nilhan Kayaman Apohan, Erdinç Babuç, Gökay Gün

引用次数: 0

Abstract

Injectable hydrogels play an important role in tissue engineering as a filling and repairing material. This study aimed to develop a new injectable hydrogel based on hyaluronic acid (HA) and quince seed gum (QSG) and investigate the effect of QSG on hydrogel performance. The amount of unreacted 1,4-Butanediol diglycidyl ether is maintained at an undetectable level for HA-QSG hydrogels. Amino acid analysis showed that the HA-QSG hydrogel had rich amino acid concentrations of leucine, arginine, and valine. After thermal sterilization, the elastic modulus of HA-QSG gels for dermal and intraarticular filler applications is 63 Pa and 92 Pa, respectively. Pore size was found below 200 μm and the dense homogeneous pore structure was observed.

查看原文本刊更多论文

榅桲籽胶（QSG）对可注射透明质酸水凝胶流变学、形态学和力学性能的影响。

可注射水凝胶作为填充和修复材料在组织工程中发挥着重要作用。本研究旨在开发一种基于透明质酸（HA）和榅桲籽胶（QSG）的新型可注射水凝胶，并研究 QSG 对水凝胶性能的影响。HA-QSG 水凝胶中未反应的 1,4-丁二醇二缩水甘油醚的含量保持在检测不到的水平。氨基酸分析表明，HA-QSG 水凝胶富含亮氨酸、精氨酸和缬氨酸。经过热消毒后，用于皮肤和关节内填充物的 HA-QSG 水凝胶的弹性模量分别为 63 Pa 和 92 Pa。孔径小于 200 μm，并观察到致密均匀的孔隙结构。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Turkish Journal of Chemistry 化学-工程：化工

CiteScore

2.40

自引率

7.10%

发文量

审稿时长

3 months

期刊介绍： The Turkish Journal of Chemistry is a bimonthly multidisciplinary journal published by the Scientific and Technological Research Council of Turkey (TÜBİTAK). The journal is dedicated to dissemination of knowledge in all disciplines of chemistry (organic, inorganic, physical, polymeric, technical, theoretical and analytical chemistry) as well as research at the interface with other sciences especially in chemical engineering where molecular aspects are key to the findings. The journal accepts English-language original manuscripts and contribution is open to researchers of all nationalities. The journal publishes refereed original papers, reviews, letters to editor and issues devoted to special fields. All manuscripts are peer-reviewed and electronic processing ensures accurate reproduction of text and data, plus publication times as short as possible.