Finite element simulation and experimental validation of thermal damage to isolated porcine skin tissue by femtosecond laser welding

IF 2 3区 物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS
Jun Huang, Mengshi Jia, Yanyu Li, Mintao Yan, Kehong Wang, Xiaopeng Li
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Abstract

The welding effect of the laser on skin tissue is reduced by thermal damage to skin tissue, and greater thermal damage to skin tissue caused by the laser is prevented by predicting thermal damage. In this paper, a finite element model is established for the temperature field of skin tissue scanned by a femtosecond laser to obtain the influence of laser process parameters and scanning path on the thermal damage parameters of skin tissue and the thermal damage area, and verified experimentally. The results show that the established finite element model is accurate and can accurately reflect the temperature distribution during the process of femtosecond laser welding of porcine skin tissues; used to predict the thermal damage parameters of the skin tissues and the thermal damage area; and provide guidance for the study of the femtosecond laser welding of the skin tissues process to obtain the optimal process parameters.

Abstract Image

飞秒激光焊接对离体猪皮肤组织热损伤的有限元模拟和实验验证。
通过对皮肤组织的热损伤来降低激光对皮肤组织的焊接效果,通过预测热损伤来防止激光对皮肤组织造成更大的热损伤。本文建立了飞秒激光扫描皮肤组织温度场的有限元模型,以获得激光工艺参数和扫描路径对皮肤组织热损伤参数和热损伤面积的影响,并进行了实验验证。结果表明,所建立的有限元模型精度较高,能准确反映飞秒激光焊接猪皮肤组织过程中的温度分布,用于预测皮肤组织的热损伤参数和热损伤面积,并为研究飞秒激光焊接皮肤组织过程以获得最佳工艺参数提供指导。
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来源期刊
Journal of Biophotonics
Journal of Biophotonics 生物-生化研究方法
CiteScore
5.70
自引率
7.10%
发文量
248
审稿时长
1 months
期刊介绍: The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.
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