Progress in Immune Checkpoint Inhibitor for Melanoma Therapy

IF 2.5 3区 医学 Q2 HEMATOLOGY
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引用次数: 0
用于黑色素瘤治疗的免疫检查点抑制剂的进展。
在过去十年中,黑色素瘤的治疗效果在所有癌症中最为显著,这主要归功于免疫检查点抑制剂(ICI)的开发。免疫检查点抑制剂最初是针对晚期患者开发的,现在已用于辅助治疗和新辅助治疗。最近,LAG-3 阻断抗体的开发以及 ICI 与基于 RNA 的个性化疫苗的结合继续引领着免疫治疗领域。尽管取得了这些进展,但原发性和继发性抗药性仍然是个问题,因此非常需要预测性生物标志物来优化 ICI 的使用效益/风险比。
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
86
审稿时长
6-12 weeks
期刊介绍: Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.
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