Prevalence of Xerostomia and Hyposalivation Among Individuals Attending Oral Cancer Screening in Thailand: A Cross-Sectional Study.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-06-27 eCollection Date: 2024-05-01 DOI:10.4103/jispcd.jispcd_156_23

Sutthipoach Ekkert, Krongkan Deeiam, Boworn Klongnoi, Vanvisa Sresumatchai, Kununya Pimolbutr, Siribang-On Piboonniyom Khovidhunkit

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引用次数: 0

Abstract

Aim: It has been speculated that the prevalence of xerostomia and hyposalivation might be higher among individuals attending oral cancer screening than among members of the general population. Therefore, this study investigated the prevalence of these conditions and their associated factors among individuals taking part in oral cancer screening and residing in the northeastern provinces of Thailand.

Materials and methods: This cross-sectional study recruited convenient individuals aged ≥40 years with at least one oral cancer risk factor. In total, 561 participants were included. Demographic characteristics and relevant oral cancer risk factors were recorded. A questionnaire comprising five items was used to assess xerostomia. Participants were then categorized into two groups based on the absence or presence of xerostomia. Subsequently, the stimulated salivary flow rate was assessed using the spitting technique to identify hyposalivation. Participants were then separated into two groups depending on the absence or presence of hyposalivation. Univariate and multivariate logistic regression analyses were then performed to identify factors associated with xerostomia or hyposalivation.

Results: The mean age of participants was 65.62 ± 9.70 years, and approximately 60% of participants were post-menopausal women. The prevalence of xerostomia was 43.85%, and the prevalence of hyposalivation was 61.50%. It was revealed that age ≥65 years (odds ratio [OR] = 1.57, P = 0.02) and burning sensation in the mouth (OR = 5.36, P < 0.001) were strongly associated with xerostomia. Female participants were more likely to exhibit hyposalivation (OR = 2.38, P = 0.001). Oral cancer risk factors were not associated with xerostomia or hyposalivation.

Conclusions: In this study, age ≥65 years and burning sensation were identified as risk factors for xerostomia, whereas female sex was a risk factor for hyposalivation. Dentists should be aware of both conditions. Various interventions to alleviate dry mouth symptoms might be useful for individuals with these risk factors.

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泰国口腔癌筛查人群中口腔干燥症和唾液分泌过少的患病率：一项横断面研究

目的：据推测，参加口腔癌筛查的人群中口腔干燥症和唾液分泌过少的患病率可能高于普通人群。因此，本研究调查了居住在泰国东北部省份、参加口腔癌筛查的人群中这些症状的患病率及其相关因素：这项横断面研究招募了年龄≥40 岁、至少有一个口腔癌风险因素的人。共纳入 561 名参与者。研究人员记录了人口统计学特征和相关的口腔癌风险因素。评估口腔干燥症的问卷包括五个项目。然后，根据有无口腔干燥症将参与者分为两组。随后，使用吐唾液技术评估受刺激的唾液流量，以确定唾液分泌过少。然后根据是否存在唾液分泌过少将参与者分为两组。然后进行单变量和多变量逻辑回归分析，以确定与口腔干燥症或唾液分泌过少相关的因素：参与者的平均年龄为 65.62 ± 9.70 岁，约 60% 的参与者为绝经后妇女。口腔干燥症的患病率为 43.85%，唾液分泌过少的患病率为 61.50%。研究显示，年龄≥65 岁（比值比 [OR] = 1.57，P = 0.02）和口腔灼热感（OR = 5.36，P < 0.001）与口腔干燥症密切相关。女性参与者更容易出现唾液分泌过少（OR = 2.38，P = 0.001）。口腔癌风险因素与口腔干燥症或唾液分泌过少无关：在这项研究中，年龄≥65 岁和烧灼感被认为是口腔干燥症的危险因素，而女性则是唾液分泌过少的危险因素。牙科医生应注意这两种情况。各种缓解口干症状的干预措施可能对具有这些风险因素的人有用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.