The Interaction Effect of Obesity with Sleep Duration on Urinary Incontinence in Adult Females: A Cross-Sectional Study of the NHANES Database.

IF 1.5 4区医学 Q3 UROLOGY & NEPHROLOGY

Urologia Internationalis Pub Date : 2024-01-01 Epub Date: 2024-07-24 DOI:10.1159/000540094

Xingyu Nan, Shuqin Dai, Shaojie Zhao, Ting Tian, Rui Gu

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引用次数: 0

Abstract

Introduction: This study aimed to explore the interaction between obesity and sleep duration on urinary incontinence (UI) in adult women.

Methods: Data of adult females were extracted from the National Health and Nutrition Examination Surveys (NHANES) database in 2005-2018 in this cross-sectional study. Weighted univariate and multivariate logistic regression analyses were utilized to screen covariates and investigate the associations of obesity and sleep duration with 3 types of UI, including stress urinary incontinence (SUI), urgency urinary incontinence (UUI), and mixed urinary incontinence (MUI). In addition, the interaction effect between obesity and sleep duration on UI was assessed. The evaluation indexes were odd ratios (ORs) and 95% confidence intervals (CIs), relative excess risk due to interaction (RERI), attributable proportion of interaction (AP), and synergy index (S).

Results: Among 13,692 eligible women, 6,063 had SUI, 4,370 had UUI, and 2,621 had MUI. After adjusting for the covariates, women with obesity had higher odds of SUI (OR = 1.78, 95% CI: 1.59-2.00), UUI (OR = 1.84, 95% CI: 1.63-2.06), and MUI (OR = 1.67, 95% CI: 1.48-1.88), compared with those who without obesity. Similarly, comparing to adequate sleep, sleep deprivation and hypersomnia were both significantly linked to higher odds of all types of UI (all p < 0.05). The restricted cubic spline (RCS) curves showed that there is a U-shaped association of sleep duration with UUI and MUI, respectively (all non-line p < 0.05). In addition, there was a potential synergistic effect between obesity and hypersomnia on UUI (RERI = 0.576, AP = 0.243, and S = 1.729) and that on MUI (RERI = 0.821, AP = 0.339, and S = 2.373).

Conclusions: Obesity and hypersomnia had a potential synergistic effect on UI, especially UUI and MUI. Adult women should adopt measures to keep BMI within normal range, and timely intervene hypersomnia to reduce the possible risk of UI.

查看原文本刊更多论文

肥胖与睡眠时间对成年女性尿失禁的交互影响：NHANES 数据库横断面研究。

简介：本研究旨在探讨肥胖和睡眠时间对成年女性尿失禁的影响：本研究旨在探讨肥胖和睡眠时间对成年女性尿失禁的相互作用：这项横断面研究从 2005-2018 年美国国家健康与营养调查（NHANES）数据库中提取了成年女性的数据。利用加权单变量和多变量逻辑回归分析筛选协变量，研究肥胖和睡眠时间与3种类型尿失禁（包括压力性尿失禁（SUI）、急迫性尿失禁（UUI）和混合性尿失禁（MUI））的相关性。此外，还评估了肥胖和睡眠时间对尿失禁的交互影响。评估指标为奇数比（ORs）和95%置信区间（CIs）、交互作用导致的相对超额风险（RERI）、交互作用的可归因比例（AP）和协同作用指数（S）：在 13,692 名符合条件的女性中，6,063 人患有 SUI，4,370 人患有 UUI，2,621 人患有 MUI。调整协变量后，与非肥胖女性相比，肥胖女性发生 SUI（OR=1.78，95%CI：1.59-2.00）、UUI（OR=1.84，95%CI：1.63-2.06）和 MUI（OR=1.67，95%CI：1.48-1.88）的几率更高。同样，与充足的睡眠相比，睡眠不足和嗜睡都与较高的各类 UI 发生几率显著相关（均为 P<0.05）。限制性立方样条曲线（RCS）显示，睡眠时间与尿频和多尿症分别呈 U 型关系（所有非线性 P<0.05）。此外，肥胖和嗜睡症对 UUI（RERI=0.576，AP=0.243，S=1.729）和 MUI（RERI=0.821，AP=0.339，S=2.373）有潜在的协同效应：结论：肥胖和嗜睡对尿意（尤其是 UUI 和 MUI）有潜在的协同作用。成年女性应采取措施将体重指数控制在正常范围内，并及时干预嗜睡症，以降低可能的尿失禁风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Urologia Internationalis 医学-泌尿学与肾脏学

CiteScore

3.30

自引率

6.20%

发文量

审稿时长

3-8 weeks

期刊介绍： Concise but fully substantiated international reports of clinically oriented research into science and current management of urogenital disorders form the nucleus of original as well as basic research papers. These are supplemented by up-to-date reviews by international experts on the state-of-the-art of key topics of clinical urological practice. Essential topics receiving regular coverage include the introduction of new techniques and instrumentation as well as the evaluation of new functional tests and diagnostic methods. Special attention is given to advances in surgical techniques and clinical oncology. The regular publication of selected case reports represents the great variation in urological disease and illustrates treatment solutions in singular cases.