Enhancing Coverage of Second Booster Dose of DPT Vaccine Coverage With Parental Education: A Cluster Randomized Approach.

IF 1.7 4区医学 Q2 PEDIATRICS

Indian pediatrics Pub Date : 2024-10-15 Epub Date: 2024-07-23

Rangasai Anirudh Neeli, Amit Kumar Satapathy, Arvind Kumar Singh, Bhagirathi Dwibedi

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引用次数: 0

Abstract

Objective: To assess the effect of a single clinic-based educational intervention session on parents of children aged 4.5 to 5.5 years on improving the coverage of a second booster dose of the DPT vaccine. The secondary objective was to assess the coverage of second booster dose of the DPT vaccine among children aged > 6 years and to learn about the reasons behind such dropouts, if any.

Methods: The study was conducted in two phases. In the first phase, a cross-sectional study was conducted among children aged > 6 years who were attending the pediatric OPD or IPD to determine the coverage of the second booster dose of DPT vaccine and possible reasons for dropout. This was followed by a clustered randomized trial evaluating the effect of an educational intervention (clinic-based, single session) among parents of children aged 4.5 to 5.5 years for improving second DPT booster coverage.

Results: A total of 384 children were enrolled in the first phase, of which 233 (60.68%) were vaccinated. Subgroup analysis showed significant differences in the vaccine coverage between children from tribal-dominant and non-tribal-dominant districts (45.10% vs 63.06%, P = 0.01). Educational intervention resulted in higher vaccination coverage (77.24%) compared to 71.43% in the control arm (P = 0.300).

Conclusion: The current study showed low coverage for second booster of DPT vaccine. With educational intervention, the target immunization coverage could be attained early which has implications for reducing childhood morbidity due to vaccine-preventable diseases.

本刊更多论文

通过家长教育提高白喉、百日咳、破伤风三联疫苗第二加强剂量的接种率：群组随机方法。

目的评估对 4.5 至 5.5 岁儿童的家长进行一次诊所教育干预对提高白百破疫苗第二针加强剂接种率的效果。次要目标是评估 6 岁以上儿童接种第二剂白百破疫苗的覆盖率，并了解辍种的原因（如果有的话）：研究分两个阶段进行。在第一阶段，对在儿科门诊或综合门诊就诊的 6 岁以上儿童进行了横断面研究，以确定白百破疫苗第二剂加强接种的覆盖率和辍种的可能原因。随后又进行了一项分组随机试验，评估在 4.5 至 5.5 岁儿童的家长中开展教育干预（以门诊为基础，单次课程）的效果，以提供咨询和视听信息，提高白喉、百日咳、破伤风三联疫苗第二次加强接种的覆盖率：第一阶段共有 384 名儿童参加，其中 233 人（60.68%）接种了疫苗。分组分析表明，部落占主导地位的地区和非部落占主导地位的地区的儿童在疫苗接种覆盖率上存在明显差异（45.10% vs 63.06%，P = 0.01）。教育干预的疫苗接种率（77.24%）高于对照组的 71.43%（P = 0.300）：本研究显示，白百破疫苗第二加强针的接种率较低。通过教育干预，可以尽早达到目标免疫接种覆盖率，这对降低疫苗可预防疾病导致的儿童发病率具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian pediatrics 医学-小儿科

CiteScore

3.30

自引率

8.70%

发文量

344

审稿时长

3-8 weeks

期刊介绍： The general objective of Indian Pediatrics is "To promote the science and practice of Pediatrics." An important guiding principle has been the simultaneous need to inform, educate and entertain the target audience. The specific key objectives are: -To publish original, relevant, well researched peer reviewed articles on issues related to child health. -To provide continuing education to support informed clinical decisions and research. -To foster responsible and balanced debate on controversial issues that affect child health, including non-clinical areas such as medical education, ethics, law, environment and economics. -To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible and enjoyable to read.