Frailty as a Risk Factor for Depression after COVID-19 Hospital Admission.

IF 2.1 Q3 GERIATRICS & GERONTOLOGY
Isabel María Soler-Moratalla, Sergio Salmerón, Silvia Lozoya-Moreno, Ana María Hermosilla-Pasamar, Antonio Henández-Martínez, Julián Solís-García Del Pozo, Margarita Escribano-Talaya, Maria Antonia Font-Payeras, Francisco García-Alcaraz
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引用次数: 0

Abstract

Background: This work aims to establish the relationship between depression and epidemiological or imaging variables, frailty, and cognitive status in patients who suffered hospital admission for COVID-19.

Methods: A longitudinal observational study investigated 72 patients admitted for COVID-19 to a hospital in Spain. Patients were evaluated at discharge and six months later. Clinical, analytical, and imaging variables were collected. A neurocognitive, nutritional, and frailty (FRAIL scale) assessment of the included patients was carried out. The risk of depression was considered for a result above 5 points on the PHQ-9 scale.

Results: The variables that were significantly related to the risk of depression 6 months after admission for COVID-19 were frailty (p = 0.006 for pre-frail and p = 0.001 for frail), small-vessel vascular disease in imaging tests (p = 0.033), vitamin D level (p = 0.006), and taking antidepressants (p = 0.011). Factors that were negatively associated with the presence of depression 6 months after discharge were a higher score on the CAMCOG cognitive scale (p = 0.041) and older age (p = 0.006).

Conclusions: Frailty worsened the score on the PHQ-9 depression scale in patients who required hospital admission for SARS-CoV-2 infection. It is important to implement prevention measures both for frailty and depression in these patients.

体弱是 COVID-19 入院后抑郁的风险因素。
背景:本研究旨在确定因 COVID-19 入院患者的抑郁与流行病学或影像学变量、虚弱程度和认知状态之间的关系:本研究旨在确定因 COVID-19 入院患者的抑郁与流行病学或影像学变量、虚弱程度和认知状态之间的关系:一项纵向观察研究调查了西班牙一家医院收治的 72 名 COVID-19 患者。患者在出院时和六个月后接受了评估。收集了临床、分析和影像学变量。对纳入研究的患者进行了神经认知、营养和虚弱程度(FRAIL量表)评估。PHQ-9量表的结果超过5分,则有可能患上抑郁症:结果:与 COVID-19 入院 6 个月后抑郁风险明显相关的变量有:虚弱(虚弱前 p = 0.006,虚弱后 p = 0.001)、影像检查中的小血管疾病(p = 0.033)、维生素 D 水平(p = 0.006)和服用抗抑郁药(p = 0.011)。与出院 6 个月后出现抑郁负相关的因素是 CAMCOG 认知量表得分较高(p = 0.041)和年龄较大(p = 0.006):结论:因感染 SARS-CoV-2 而需要入院治疗的患者中,体弱会增加 PHQ-9 抑郁症量表的得分。对这些患者实施虚弱和抑郁的预防措施非常重要。
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来源期刊
Geriatrics
Geriatrics 医学-老年医学
CiteScore
3.30
自引率
0.00%
发文量
115
审稿时长
20.03 days
期刊介绍: • Geriatric biology • Geriatric health services research • Geriatric medicine research • Geriatric neurology, stroke, cognition and oncology • Geriatric surgery • Geriatric physical functioning, physical health and activity • Geriatric psychiatry and psychology • Geriatric nutrition • Geriatric epidemiology • Geriatric rehabilitation
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