Western lifestyle, metaflammation and the cell of origin of colon cancer

IF 45.9 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Nature Reviews Gastroenterology &Hepatology Pub Date : 2024-07-24 DOI:10.1038/s41575-024-00964-7

Mathijs P. Verhagen, Mark Schmitt, Riccardo Fodde

引用次数: 0

Abstract

Western lifestyles cause a low-grade but chronic and metabolic inflammation (or metaflammation), which might prime committed cell lineages to initiate colon tumorigenesis. At-risk individuals might include cases of early-onset colon cancer, the incidence of which has risen dramatically in the past few decades.

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西方生活方式、元炎症和结肠癌的起源细胞

西方生活方式会导致一种低度但慢性的代谢性炎症（或称变态反应炎症），这种炎症可能会促使细胞系开始形成结肠肿瘤。高危人群可能包括早发结肠癌病例，这种疾病的发病率在过去几十年中急剧上升。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Gastroenterology &Hepatology 医学-胃肠肝病学

CiteScore

52.30

自引率

0.60%

发文量

147

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Gastroenterology & Hepatology aims to serve as the leading resource for Reviews and commentaries within the scientific and medical communities it caters to. The journal strives to maintain authority, accessibility, and clarity in its published articles, which are complemented by easily understandable figures, tables, and other display items. Dedicated to providing exceptional service to authors, referees, and readers, the editorial team works diligently to maximize the usefulness and impact of each publication. The journal encompasses a wide range of content types, including Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements, all pertinent to gastroenterologists and hepatologists. With its broad scope, Nature Reviews Gastroenterology & Hepatology ensures that its articles reach a diverse audience, aiming for the widest possible dissemination of valuable information. Nature Reviews Gastroenterology & Hepatology is part of the Nature Reviews portfolio of journals.