{"title":"BioEssays 8/2024","authors":"","doi":"10.1002/bies.202470012","DOIUrl":null,"url":null,"abstract":"<p>Eukaryotic chromosome ends are characterized by specialized structures, namely telomeres. Telomeric DNA is usually rich in guanines and is able to form four-stranded G-quadruplexes. In article 2300229, So Young Joo et al. review how dynamic interactions between G-quadruplexes and the tumor suppressor BRCA2 influence telomere replication.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure>\n </p>","PeriodicalId":9264,"journal":{"name":"BioEssays","volume":"46 8","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bies.202470012","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BioEssays","FirstCategoryId":"99","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/bies.202470012","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Eukaryotic chromosome ends are characterized by specialized structures, namely telomeres. Telomeric DNA is usually rich in guanines and is able to form four-stranded G-quadruplexes. In article 2300229, So Young Joo et al. review how dynamic interactions between G-quadruplexes and the tumor suppressor BRCA2 influence telomere replication.
期刊介绍:
molecular – cellular – biomedical – physiology – translational research – systems - hypotheses encouraged
BioEssays is a peer-reviewed, review-and-discussion journal. Our aims are to publish novel insights, forward-looking reviews and commentaries in contemporary biology with a molecular, genetic, cellular, or physiological dimension, and serve as a discussion forum for new ideas in these areas. An additional goal is to encourage transdisciplinarity and integrative biology in the context of organismal studies, systems approaches, through to ecosystems, where appropriate.